Q7P1R4
Gene name |
pgi1 |
Protein name |
Glucose-6-phosphate isomerase 1 |
Names |
GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase 1, PHI 1 |
Species |
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) |
KEGG Pathway |
cvi:CV_0149 |
EC number |
5.3.1.9: Interconverting aldoses and ketoses |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7P1R4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7P1R4-F1 | Predicted | AlphaFoldDB |
No variants for Q7P1R4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7P1R4 | |||||
No associated diseases with Q7P1R4
4 regional properties for Q7P1R4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phosphoglucose isomerase, conserved site | 263 - 276 | IPR018189-1 |
| conserved_site | Phosphoglucose isomerase, conserved site | 495 - 512 | IPR018189-2 |
| domain | Phosphoglucose isomerase, SIS domain 1 | 118 - 282 | IPR035476 |
| domain | Phosphoglucose isomerase, SIS domain 2 | 330 - 518 | IPR035482 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.3.1.9 | Interconverting aldoses and ketoses |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| carbohydrate derivative binding | Binding to a carbohydrate derivative. |
| glucose-6-phosphate isomerase activity | Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| gluconeogenesis | The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
| glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSELTELPAW | QALWDHFAEA | KHLHMRDLFA | ADPGRAERYS | LEVGGLFLDY | SKNRITDATL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LGLMELAREA | GLPARIKAMF | KGEKINRTEN | RAVLHVALRN | RTNSPIRVDG | EDVMPKVNSV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LERMGKFAHA | VRSGDWLGFT | NQPITDIVNI | GIGGSDLGPL | MVCSALKPFG | HPRLNMHFVS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NVDGAQLKET | LKKVHPETTL | FVVESKTFTT | QETLTNALTA | REWFLSHARD | EGAVAKHFVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VSTNQKAVAE | FGIDPANMFE | FWNWVGGRYS | LWSAIGLPIM | LYLGEENFTE | LLNGAHIMDQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HFMNAPFEQN | MPVLLAMIGV | WYINYYGGGS | HVIAPYDQYL | HRLPAFIQQL | DMESNGKQVT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LSGQPVDFET | APIIWGETGI | NGQHAFFQLL | HQGTHISPID | LIASLGNRAS | LPGHHEILLA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NVFAQAEAFM | RGKTADEVRA | ELAEQGLSGE | EMEALVPHKV | FGGNRPTNTL | LMSRLDPRNL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GSLIALYEHK | IFVQGVIWHI | NSFDQWGVEL | GKQLAKTIHA | ELTGKLEQAE | HDSSTRRLIQ |
| LYRKANG |