Q7NY10

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
KEGG Pathway
cvi:CV_1466
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

673-722 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7NY10

Entry ID Method Resolution Chain Position Source
AF-Q7NY10-F1 Predicted AlphaFoldDB

No variants for Q7NY10

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NY10

No associated diseases with Q7NY10

8 regional properties for Q7NY10

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 23 - 152 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 333 - 465 IPR001247-2
domain S1 domain 627 - 700 IPR003029
domain K Homology domain 560 - 625 IPR004087
domain K Homology domain, type 1 565 - 622 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 155 - 218 IPR015847
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 250 - 329 IPR015848
domain RNA-binding domain, S1 628 - 700 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNQDRETLVF NKITKTFQFG RQTVTLETGE IARQASGSVV VSVDDTVVMV SVVGGKNVKP
70 80 90 100 110 120
GQDFFPLTVD YLERTYAAGK IPGGFFKREG KQSEKEVLTS RLIDRPIRPL FPEGFYHDVQ
130 140 150 160 170 180
IVATVLSLNP EVDSDIPAMI GASAALAISG LPFAGPIGAA RVGYANGEYI LNPTKTELQT
190 200 210 220 230 240
SQMDLVVAGT SRAVLMVESE AKELPEAVML GAVVFGHEQM QAAIKAINEL ADEVNPVMFD
250 260 270 280 290 300
WAAPAKDEAL IAQIRGIAGE KLAEAFRLRQ KQARTVAINE AWDAVKAGLI NEETDTLKAN
310 320 330 340 350 360
EIKGIFKSLE AEIVRGQILA GEARIDGRDT RTVRPISIRN NVLPRTHGSA LFTRGETQAL
370 380 390 400 410 420
VVATLGTKQD EQIIDALAGE YTERFMLHYN FPPYSTGEAG RMGPPKRREI GHGRLAKRAL
430 440 450 460 470 480
VAVLPPEDEF GYSMRVVSEI TESNGSSSMA SVCGGCLSLL SAGVPLKAHV AGIAMGLILE
490 500 510 520 530 540
GNRFAVLTDI LGDEDHLGDM DFKVAGTAAG VTALQMDIKI QGITKEIMQV ALEQAKEGRL
550 560 570 580 590 600
HILGLMKEAV DGPQELSAHA PRLYVMKINP EKIREVIGKG GETIRSITKD TGCEINIEED
610 620 630 640 650 660
GTITIASVSS EGAEAAKKRI EEITVEVEVG KVYEGTVVKI LDNNVGAIVS ILPGKDGLVH
670 680 690 700 710 720
ISQIANERIK NVSDYLKEGQ VVKVKAIEMD DRGRIRLSIK ALLEEEAKTA QATADAFGLK
TQ