Q7NXX7

PR
Gene name
astD
Protein name
N-succinylglutamate 5-semialdehyde dehydrogenase
Names
Succinylglutamic semialdehyde dehydrogenase, SGSD
Species
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
KEGG Pathway
cvi:CV_1499
EC number
1.2.1.71: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7NXX7

Entry ID Method Resolution Chain Position Source
AF-Q7NXX7-F1 Predicted AlphaFoldDB

No variants for Q7NXX7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NXX7

No associated diseases with Q7NXX7

3 regional properties for Q7NXX7

Type Name Position InterPro Accession
domain Aldehyde dehydrogenase domain 10 - 460 IPR015590
conserved_site Aldehyde dehydrogenase, cysteine active site 271 - 282 IPR016160
conserved_site Aldehyde dehydrogenase, glutamic acid active site 243 - 250 IPR029510

Functions

Description
EC Number 1.2.1.71 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
succinylglutamate-semialdehyde dehydrogenase activity Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH.

2 GO annotations of biological process

Name Definition
arginine catabolic process to glutamate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.
arginine catabolic process to succinate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSLFIDGKW LAGDGEAMAK TNPADNAPLW QGRAASAAQV DAAVRAARAA FPAWARMGLE
70 80 90 100 110 120
ERAKVVRRFG ERLTERKAEL ARVIAQETGK PLWEATTEVT TMVGKIDISL KALAERTGER
130 140 150 160 170 180
AAAMGDAQAV LRHKPHGVVA VFGPYNFPGH LPNGHIVPAL LAGNSVIFKP SELTPWTAEE
190 200 210 220 230 240
TVKLWAEAGL PAGVIGLVQG AKDTGVALAG HEGLDGLFFT GSSATGALLH KQFSGRPDKI
250 260 270 280 290 300
LALEMGGNNP LIVGEVADVD GAVHHVIQSA FVSAGQRCTC ARRLLVPQGE WGDAFVARLV
310 320 330 340 350 360
EVAGKLRVGK FDAEPAPFLG AVISNAAADA LLKAQDDLVA AGGTPLLAMR RLEEGAAMLT
370 380 390 400 410 420
PGIIDTTAAV RPDEEFFGPL LQVIRYADFD QAIAIANDTR FGLAGGVLSD SRELYDRYWL
430 440 450 460 470 480
ESRAGVVNWN KPLTGASSAA PFGGIGASGN HRPSAYYAAD YCAYPVASLE CDSLALPAQL
SPGIVL