Q7NTZ8

PR
Gene name
nudC
Protein name
NAD-capped RNA hydrolase NudC
Names
DeNADding enzyme NudC, NADH pyrophosphatase
Species
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
KEGG Pathway
cvi:CV_2905
EC number
3.6.1.22: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

50-121 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7NTZ8

Entry ID Method Resolution Chain Position Source
AF-Q7NTZ8-F1 Predicted AlphaFoldDB

No variants for Q7NTZ8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NTZ8

No associated diseases with Q7NTZ8

3 regional properties for Q7NTZ8

Type Name Position InterPro Accession
domain NUDIX hydrolase domain 133 - 256 IPR000086
domain Zinc ribbon, NADH pyrophosphatase 101 - 132 IPR015376
conserved_site NUDIX hydrolase, conserved site 167 - 188 IPR020084

Functions

Description
EC Number 3.6.1.22 In phosphorus-containing anhydrides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
manganese ion binding Binding to a manganese ion (Mn).
NAD+ diphosphatase activity Catalysis of the reaction: NAD+ + H2O = AMP + NMN.
NADH pyrophosphatase activity Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.
RNA NAD-cap (NMN-forming) hydrolase activity Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+).
zinc ion binding Binding to a zinc ion (Zn).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPFELPQQPA PELPERWCVF NGSLLWLQDN QLPAQPPAGC ALTGQRFLGI HEGSNLFLAD
70 80 90 100 110 120
LVGDMPAQAG EWLPLRPALL AMPMAQVQAA ARAAQLRQFF HSHRFCGHCA TPLAVSADQL
130 140 150 160 170 180
GRHCPSCGQV YYPRISPAMM VLVRRGRELL LARSPHFAPG MYSALAGFVE PGETLEECVH
190 200 210 220 230 240
RETWEEVGVK VKNLRYAFSQ SWPFPHSLML AFIAEYDGGD IRPQEGEIED AGWFDIDALP
250 260
GLPMPISIAH RLIRHACDRI RDLEA