Q7NRK0

PR
Gene name
arcB
Protein name
Ornithine carbamoyltransferase, catabolic
Names
OTCase
Species
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
KEGG Pathway
cvi:CV_3781
EC number
2.1.3.3: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

48-119 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7NRK0

Entry ID Method Resolution Chain Position Source
AF-Q7NRK0-F1 Predicted AlphaFoldDB

No variants for Q7NRK0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NRK0

No associated diseases with Q7NRK0

3 regional properties for Q7NRK0

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 277 - 286 IPR020557
domain Fumarate lyase, N-terminal 9 - 302 IPR022761
domain Argininosuccinate lyase, C-terminal 367 - 433 IPR029419

Functions

Description
EC Number 2.1.3.3 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
amino acid binding Binding to an amino acid, organic acids containing one or more amino substituents.
ornithine carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.

2 GO annotations of biological process

Name Definition
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
arginine catabolic process to ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFNLRNRNF LKMLDFTPRE IRYLLDLSRD LKRAKYSGTE QQHLKGKNVA LIFEKTSTRT
70 80 90 100 110 120
RCAFEVACFD QGANVSYIGP SGSQIGHKES MKDTARVLGR MYDAIEYRGY SQDMVEHELA
130 140 150 160 170 180
AYAGVPVYNG LTDEYHPTQM LADVLTMWEH SDKPISQISY TYLGDARNNM GNSLLVIGSK
190 200 210 220 230 240
LGMDVRIGAP KHLWPTDELV AECREIAKRT GARITLTEDP KEAVKGTDFI HTDVWVSMGE
250 260 270 280 290 300
PAEVWAERIR LLKPYQVNSA LMAASGNPQV KFMHCLPAFH NSETKVGKEI SAQYPELANG
310 320 330
IEVTEDVFES EACIAFEQAE NRMHTIKAIL VSTLGD