Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7NJ41

Entry ID Method Resolution Chain Position Source
AF-Q7NJ41-F1 Predicted AlphaFoldDB

No variants for Q7NJ41

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NJ41

No associated diseases with Q7NJ41

2 regional properties for Q7NJ41

Type Name Position InterPro Accession
conserved_site Ribosomal RNA adenine methylase transferase, conserved site 33 - 59 IPR020596
domain Ribosomal RNA adenine methylase transferase, N-terminal 17 - 187 IPR020598

Functions

Description
EC Number 2.1.1.182 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (adenine-N6,N6-)-dimethyltransferase activity Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.

1 GO annotations of biological process

Name Definition
rRNA methylation The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MYTLKRFGQH WLNDGAVLDR IVAAAGLACG DRVLEIGPGL GSLTARLLRQ VPVVAVEIDR
70 80 90 100 110 120
RAVAQLQRQF GGDKRFVLVE GDILREALPE PANVVVANIP YNISGPILAK LTGSLAQPIR
130 140 150 160 170 180
RFRTIVLLVQ KELGQRIAAP PGSRTYGALS VRLQYLAECE LLFEVPSHCF TPPPKVDSAV
190 200 210 220 230 240
IRLTPRPFAL QADDPAHLDA LVTRAFATRR KMLKNCLKGW VETEKLLAAF ASLDISPDAR
250 260 270
AEDLSVERFV QLSNRLAESD YPSGAARGDR RA