Q7NEK2

PR
Gene name
hemE
Protein name
Uroporphyrinogen decarboxylase
Names
UPD, URO-D
Species
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
KEGG Pathway
gvi:gll3877
EC number
4.1.1.37: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7NEK2

Entry ID Method Resolution Chain Position Source
AF-Q7NEK2-F1 Predicted AlphaFoldDB

No variants for Q7NEK2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NEK2

No associated diseases with Q7NEK2

4 regional properties for Q7NEK2

Type Name Position InterPro Accession
domain Helicase, C-terminal 297 - 449 IPR001650
domain DEAD/DEAH box helicase domain 95 - 256 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 89 - 284 IPR014001
domain RNA helicase, DEAD-box type, Q motif 70 - 98 IPR014014

Functions

Description
EC Number 4.1.1.37 Carboxy-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
uroporphyrinogen decarboxylase activity Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.

1 GO annotations of biological process

Name Definition
protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQSLLLDAA RSKPVARPPV WMMRQAGRYM AEYRALRDKY GFKERCENPD LAVEISLQPF
70 80 90 100 110 120
RAFRPDGVIM FSDILTPFDG MGIPFELVES RGPVIDPPIR TREQVEAVRP LDPEASLAFV
130 140 150 160 170 180
RTILQTLRRE VGEAATVLGF VGAPWTLAAY AVEGKSSKDY ALIKQMAFSE PDLLHALLTK
190 200 210 220 230 240
FADAIARYVI FQIDSGAQAV QLFDTWAGQL NPADYRAFAL PYERRIVEQV RQVHPETPLI
250 260 270 280 290 300
LYINHSAGLL RHVGESGVDV MSLDWTVDMA EARAILGPDM AVQGNLDPCV LLGDQAQIRS
310 320 330 340
RILDIVEKAG PTGHIMNLGH GILPSTPEDN ARFFFETVKS LAPVSAR