Q7NDF7

PR
Gene name
rpoC2
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
KEGG Pathway
gvi:glr4278
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

349-420 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7NDF7

Entry ID Method Resolution Chain Position Source
AF-Q7NDF7-F1 Predicted AlphaFoldDB

No variants for Q7NDF7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7NDF7

No associated diseases with Q7NDF7

2 regional properties for Q7NDF7

Type Name Position InterPro Accession
domain RNA polymerase Rpb1, domain 5 172 - 1173 IPR007081
domain RNA polymerase Rpb1, domain 4 91 - 160 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQEPQPKFI NRKIDKKGLG KLISWAFSHY GTARTALLAD NLKNLGFRFA TRGAVSISVE
70 80 90 100 110 120
DLQVPDSKVN ILETAEREIQ RAEERFTRGE ITEVERFQKV IDTWAGATQE LTEGVKENFQ
130 140 150 160 170 180
ERNPLNSVGM MAFSGARGNL SQVRQLVGMR GLMANPQGEI IDLPIKANFR EGLNVTEYII
190 200 210 220 230 240
SSYGARKGLV DTALRTADSG YLTRRLVDVS QDVIVREEDC TTQRGIFLGS LRDGDKMIVS
250 260 270 280 290 300
LEERLVGRVA GRDVVHPVTG EVLAPRNTQF DYDSAARIAR SGVDAVMVRS PLTCEANRSV
310 320 330 340 350 360
CRMCYGWSLA HSHLVDIGEA VGIIAAQSIG EPGTQLTMRT FHTGGVFTGE VAKPLKAPFD
370 380 390 400 410 420
GKIKFSSALK ARPMRTRHGD DAYQADQAGT MSLEGSDGKK ETVTITPGSL LLVRDGQRIE
430 440 450 460 470 480
AGTMYAELAL VGKTARKSTE KAQKEVFSDL AGEIKFADLV PEVKTDRQGN ETQYASRLGL
490 500 510 520 530 540
LWVLSGEVYN LPPGAETSLE RGGKVEQGGV IAETRLVTEH GGGVRLKEQD AKGGREVEII
550 560 570 580 590 600
TASVMLDKAI VHEEKSQGRE HYSLETDNGQ VFALKVSPGT KVNNGQVVAE RVDDRYMTKS
610 620 630 640 650 660
GGLIKYSEGV EVAKARGKQG YEVLKGGTLL WIPEETHEVN KDISLLEVED GQYVEAGVQV
670 680 690 700 710 720
VKDIYCLTSG VVAIAQRNDI LREVVIKPGE LHLLDAPSDL KVAHESFAYP GTEVIPGVVT
730 740 750 760 770 780
TDLRYVEQVE TPEGLAVLLR PVEEFPVPDE PDAPSQEASQ QAGSSIRLRG MQRIPYRDGD
790 800 810 820 830 840
RVKAIDGIEL LKTQLVLEIT DQAAQLAADI EFVPDEKDPS MVRLQLVILE TLLIRRDVAA
850 860 870 880 890 900
DLLHGSTLTH ILVKDGERIG PGAIIARTEI LAKQAGTVRG ISRVGQTVRR ILLVTQSDLV
910 920 930 940 950 960
NVPVEGTLTV KPGDLLRAGD KLAKDFASPE SGQVVLAESG RVVVRIGRPY LVSGGAILLV
970 980 990 1000 1010 1020
VDGDLIQRGD NLALLVFERA KTGDIIQGLP RVEELLEGRK PKEMCVLVER PGKVQITQMP
1030 1040 1050 1060 1070 1080
DESYQVSVVE DDGGVTNYPI IGQSLVVVDG QQVQTGESIT DGPSNPHDIL RIFTAREGLQ
1090 1100 1110 1120 1130 1140
KGIESVQRYL VNEVQQVYRS QGVEIHDKHI EIIVRQMTSK VRVEDGGDTT FLPGELVELR
1150 1160 1170 1180 1190 1200
QIEQVNEAMA VTGGAPADCT PVLLGITKAS LNTDSFISAA SFQETTRVLT EAAIEGKSDW
1210 1220 1230 1240 1250 1260
LRGLKENVII GRLIPAGTGF NAYEEAEEVI EDDELIDDTL GLRTVGVAFA GDDDFVEEED
ED