Q7N964

PR
Gene name
thiE
Protein name
Thiamine-phosphate synthase
Names
TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase
Species
Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
KEGG Pathway
plu:plu0485
EC number
2.5.1.3: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-189 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7N964

Entry ID Method Resolution Chain Position Source
AF-Q7N964-F1 Predicted AlphaFoldDB

No variants for Q7N964

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7N964

No associated diseases with Q7N964

1 regional properties for Q7N964

Type Name Position InterPro Accession
domain Thiamine phosphate synthase/TenI 18 - 206 IPR022998

Functions

Description
EC Number 2.5.1.3 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
thiamine-phosphate diphosphorylase activity Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.

2 GO annotations of biological process

Name Definition
thiamine biosynthetic process The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
thiamine diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNNLPNAPFA PTEHRLGLYP VVDSLAWISR LLQTGVTTIQ LRIKDLPEDQ VEEEIQQAIM
70 80 90 100 110 120
LGRQYNARLF INDYWRLAIK HGAYGVHLGQ EDLVIADLNA IQKTGLRLGI STHDEQELAR
130 140 150 160 170 180
AKSLRPSYIA LGHIFPTTTK AMPSSPQGVE ALKRQVENTP DYSTVAIGGI SLERVPDVIA
190 200 210
TGVGSVALVS AITKAKDWRQ ATAQLLYLVE GIELKG