Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7N621

Entry ID Method Resolution Chain Position Source
AF-Q7N621-F1 Predicted AlphaFoldDB

No variants for Q7N621

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7N621

No associated diseases with Q7N621

2 regional properties for Q7N621

Type Name Position InterPro Accession
domain Nicotinate phosphoribosyltransferase, N-terminal domain 13 - 131 IPR040727
domain Nicotinate/nicotinamide phosphoribosyltransferase 172 - 398 IPR041525

Functions

Description
EC Number 6.3.4.21 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
nicotinate phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate.

1 GO annotations of biological process

Name Definition
NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLDATPIIK SLLDTDAYKL HMQQAVYHRY SHMPVVAEFR CRGDELLGEY ATELRHQVNM
70 80 90 100 110 120
MADLALTDAE FNYLSSLPFF KADYLDWLKT FRFNPQQVNI SVTNGGQLAI HISGLWYEVI
130 140 150 160 170 180
MWEVPLLALI SELIHRHHSP DNTVENAVNQ LRKLIKLFYQ HAENEGIDLS SFKLMDFGTR
190 200 210 220 230 240
RRFSHRVQHA VVSELQQHFP YLIGTSNYQL AQQLGLPPVG TQAHEWFQAH QQISPDLASS
250 260 270 280 290 300
QREALQSWLK EYPNQLGIAL TDCITMDAFL RDFDAQFAKN YQGLRHDSGD PVQWGEKAIA
310 320 330 340 350 360
HYQKLGIDPM TKTLVFSDSL DFQKALALYR HFHNRINLIF GIGTQLTCNI PGVKPLNIVI
370 380 390 400
KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQV KQAC