Q7MV19

PR
Gene name
feoB1
Protein name
Fe(2+) transport protein A/Fe(2+) transporter FeoB fusion protein
Names
Ferrous iron transport protein B
Species
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
KEGG Pathway
pgi:PG_1294
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

43-151 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7MV19

Entry ID Method Resolution Chain Position Source
AF-Q7MV19-F1 Predicted AlphaFoldDB

No variants for Q7MV19

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7MV19

No associated diseases with Q7MV19

10 regional properties for Q7MV19

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 127 - 282 IPR005225
domain GTP binding domain 129 - 149 IPR006073-1
domain GTP binding domain 150 - 168 IPR006073-2
domain GTP binding domain 196 - 214 IPR006073-3
domain Ferrous iron transporter FeoA domain 1 - 73 IPR007167
domain Ferrous iron transport protein B, C-terminal 586 - 638 IPR011640
domain Nucleoside transporter/FeoB GTPase, Gate domain 482 - 576 IPR011642-1
domain Nucleoside transporter/FeoB GTPase, Gate domain 643 - 815 IPR011642-2
domain FeoB-type guanine nucleotide-binding (G) domain 126 - 289 IPR030389
domain FeoB, cytosolic helical domain 301 - 396 IPR041069

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ferrous iron transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
GTP binding Binding to GTP, guanosine triphosphate.
transition metal ion binding Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

1 GO annotations of biological process

Name Definition
iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLSELHTGD QAVIVRVEGR GVFRKRILEM GFVHGKTITV VQCAPLRDPV YYRIMDYNVS
70 80 90 100 110 120
LRREDAAKIE VELISSNATS SPASNDIGEQ SANPDSNESI PTNPTEDISA KTKSEIEIEV
130 140 150 160 170 180
KPNGHVIRVA LIGNPNCGKT SIFNRASGAH EHVGNYSGVT VEAKEGLFRH GDYKIEIIDL
190 200 210 220 230 240
PGTYSLSPYS PEELYIRQYL SEETRPDLVL NVVDTCNLER NLYLTLQLKE MGLPVVIALN
250 260 270 280 290 300
MFDEFEKKGD TFDYPALSAM LGIPMVPTVG RTGQGLPELF DTLISIHEGR NKIIRPIRIN
310 320 330 340 350 360
YGSIIEPAVE ALTEKINNQL SLPYSLPARY IAVKLLEGDK EMNRFVGEQP KGLFILSARD
370 380 390 400 410 420
FALREIDEHL TVARDAESII TDQRYGFIAG ALKETYRSSY KQLKTLTDKI DHIVTHRVLG
430 440 450 460 470 480
FPLFLLFMFI MFEATFVLGR YPMDWIEAGV GWIGSMVNTF MPDGSFKDLI VDGVIGGVGG
490 500 510 520 530 540
VIVFLPNILI LYFFISLMED SGYMARAAFI MDKIMHRMGL HGKSFIPLIM GFGCNVPAIM
550 560 570 580 590 600
ATRTIESKQS RMITMLVTPL MSCSARLPVY LLLAGAFFPD SAGLVLFGLY FLGILLAVLL
610 620 630 640 650 660
ARLFKKTLFK VEDVPFVMEL PPYRMPTSRS VIVHMWNKAA QYLRKMGSII LLASIVIWFL
670 680 690 700 710 720
SYYPRYSEEA VLISQIEQIE GNPQLDEEKK TSQIEELNRK AHIEQQEQSY IGRFGKAVQP
730 740 750 760 770 780
VLAPIGFDWK MSVSLLTGMA AKEVVVSTLG VIYTGDSDDS DEAARRLGER IREDRDAEGN
790 800 810 820 830 840
HTFSPIIALA LMAFVLIYFP CIATVVAIGR ESGHWKWAVF SIIYSCSLAW IVSFLIYRIG
ILFF