Q7MQ31

PR
Gene name
ubiB
Protein name
Probable protein kinase UbiB
Names
Ubiquinone biosynthesis protein UbiB
Species
Vibrio vulnificus (strain YJ016)
KEGG Pathway
vvy:VV0179
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

443-524 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7MQ31

Entry ID Method Resolution Chain Position Source
AF-Q7MQ31-F1 Predicted AlphaFoldDB

No variants for Q7MQ31

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7MQ31

1 associated diseases with Q7MQ31

[MIM: 619423]: Combined oxidative phosphorylation deficiency 53 (COXPD53)

An autosomal recessive mitochondrial disorder characterized by global developmental delay, hypomyelination, cerebral atrophy, microcephaly, liver dysfunction, and recurrent autoinflammation. {ECO:0000269|PubMed:33945503}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID
  • An autosomal recessive mitochondrial disorder characterized by global developmental delay, hypomyelination, cerebral atrophy, microcephaly, liver dysfunction, and recurrent autoinflammation. {ECO:0000269|PubMed:33945503}. Note=The disease is caused by variants affecting the gene represented in this entry.

4 regional properties for Q7MQ31

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 439 - 673 IPR003439
domain AAA+ ATPase domain 464 - 650 IPR003593
domain ABC transporter type 1, transmembrane domain 109 - 402 IPR011527
conserved_site ABC transporter-like, conserved site 576 - 590 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.

3 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
regulation of ubiquinone biosynthetic process Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTPTELKRLY RIIKVQLEYG LDDLLPDHQL AKAPRWMRKS LFWLKNQHPE KPLGDRLRLA
70 80 90 100 110 120
LQELGPVWIK FGQMLSTRRD LFPPHIADPL ALLQDQVSPF DGALAKAQME QALGGPLETW
130 140 150 160 170 180
FSDFDLVPLA SASIAQVHTA KLKTTNQEVV LKVIRPDIRP IIDADLKLMR RMASIVAKAM
190 200 210 220 230 240
PEARRLKPIE VVREYEKTLL DELDLRREAA NAIQLRRNFT DSEELYVPEV YPDFSNETVM
250 260 270 280 290 300
VSERIYGIQV SDITGLKANG TNMKLLAERG VSVFFTQVFR DSFFHADMHP GNVFVNPEHP
310 320 330 340 350 360
ENPQWIGLDC GIVGTLNSED KRYLAENFLA FFNRDYRRVA ELHVDSGWVP ADTNIDEFEF
370 380 390 400 410 420
AIRIVCEPIF AKPLCEISFG HVLLNLFNTA RRFNMEVQPQ LVLLQKTLLY VEGLGRQLYP
430 440 450 460 470 480
QLDLWETAKP FLEEWMMNQV GPKALINAIK DRAPYWAEKL PELPELLYDS LKQGKAMNQR
490 500 510 520 530 540
MDQLYQGYRA SKRQQATGKF LFGVGATLVV CSAILVDHTY EQLSLATAIA GVTFWLFSWR
AYRR