Q7MNJ0

PR
Gene name
ppk
Protein name
Polyphosphate kinase
Names
ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase
Species
Vibrio vulnificus (strain YJ016)
KEGG Pathway
vvy:VV0727
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-114 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7MNJ0

Entry ID Method Resolution Chain Position Source
AF-Q7MNJ0-F1 Predicted AlphaFoldDB

No variants for Q7MNJ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7MNJ0

No associated diseases with Q7MNJ0

6 regional properties for Q7MNJ0

Type Name Position InterPro Accession
domain Phospholipase D/Transphosphatidylase 428 - 462 IPR001736-1
domain Phospholipase D/Transphosphatidylase 585 - 615 IPR001736-2
domain Polyphosphate kinase middle domain 119 - 319 IPR024953
domain Polyphosphate kinase N-terminal domain 7 - 109 IPR025198
domain Polyphosphate kinase C-terminal domain 2 501 - 672 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 330 - 491 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

3 GO annotations of biological process

Name Definition
organophosphate metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSADKFYIEK ELSWLSFNER VLQEAADKTV PLIERIRFLG IFSNNLDEFY KVRFSDVKRR
70 80 90 100 110 120
ILINREQGGN DISKHLLSKM QSKALKLNER FDELYNELIR DMARRHIFLV NESQLDEAQQ
130 140 150 160 170 180
KWIIKYFQKE VLPHITPLML TDEIDVLQFL KDEYAYIAVE LKQQEQAKYA LLEIPTDHLP
190 200 210 220 230 240
RFIMVPEQKG KRKKTIILLD NIIRFCLNDI FRGFFDYDEL NGYAMKMTRD AEYDLRHEVE
250 260 270 280 290 300
YSLLEQMSEG LSQRLTALPV RFVYERDMPE DMLKYLCYKL KISHYDSLIP GGRYHNFKDF
310 320 330 340 350 360
IAFPNVGRDY LENKPLPPLA CADFEGYANA FDAIRNQDIL LHYPYHSFEH ITELVRQASF
370 380 390 400 410 420
DPKVVSIKIN VYRVAKNSRL MNSLIDAVHN GKRVTVVVEL QARFDEEANI EWSKRLTDAG
430 440 450 460 470 480
VHVIFGVPGM KIHAKLLLIT RREEQGFVRY AHIGTGNFHE RTARIYTDFS LLTADQELAA
490 500 510 520 530 540
EVRGVFSYIM NPFRPIKFRH LIVSPRNSRS QLYRLLDREI HNAQAGKKAS ITLKVNNLVD
550 560 570 580 590 600
KGLISKLYAA SSAGVKIRMI IRGMCSLVPG LEGISENIEI ISIIDRFLEH PRVLVVHNDG
610 620 630 640 650 660
DPQVFISSAD WMERNIDNRI EVMSPVRDAR IKQRIIDILS IQFTDTVKAR RIDKEMSNNY
670 680 690
VERGNRKKIR SQIAIYDYLK NVEKHTRKQK GQVEPNDNNE