Q7MBA6

PR
Gene name
acs
Protein name
Acetyl-coenzyme A synthetase
Names
AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme
Species
Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
KEGG Pathway
plu:plu0074
EC number
6.2.1.1: Acid--thiol ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

591-651 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7MBA6

Entry ID Method Resolution Chain Position Source
AF-Q7MBA6-F1 Predicted AlphaFoldDB

No variants for Q7MBA6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7MBA6

No associated diseases with Q7MBA6

4 regional properties for Q7MBA6

Type Name Position InterPro Accession
domain AMP-dependent synthetase/ligase domain 85 - 518 IPR000873
conserved_site AMP-binding, conserved site 257 - 268 IPR020845
domain AMP-binding enzyme, C-terminal domain 527 - 605 IPR025110
domain Acetyl-coenzyme A synthetase, N-terminal domain 23 - 79 IPR032387

Functions

Description
EC Number 6.2.1.1 Acid--thiol ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
acetate-CoA ligase activity Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
AMP binding Binding to AMP, adenosine monophosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
acetyl-CoA biosynthetic process from acetate The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.
chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKIMKHPIP IAIAEHALMN EQQYQQDYQL SLQDPDRFWG EKGKIVDWIK PYTKVKNTSF
70 80 90 100 110 120
DPGHINIRWF EDGTLNLSAN CLDRHLKERG EQTAIIWEGD DPTESKAITY RELHHDVCQF
130 140 150 160 170 180
ANVLKNMGIK KGDVVAIYMP MVPEAAVAML ACARIGAIHS VIFAGFSPDA VSGRIIDSNT
190 200 210 220 230 240
KLVITADEGL RAGRTIPLKK NVDDALNNAA VVNVSNVIVF KRTGNIGHWQ SGRDLWWHEL
250 260 270 280 290 300
VADASADCPV EEINAEDPLF ILYTSGSTGK PKGVLHTTGG YLVYASLTFK YVFDYQPGEV
310 320 330 340 350 360
YWCTADVGWV TGHSYLLYGP LSCGAITLMF EGVPNYPAVN RLSQIIDKHQ VNILYTAPTA
370 380 390 400 410 420
IRALMAEGDK AIEGTKRTSL RIMGSVGEPI NPEAWEWYYQ KIGNSKCPIV DTWWQTETGG
430 440 450 460 470 480
FMITPLPGAT ELKAGSATLP FFGVQPALVD NLGEQLEGVC EGNLVITDSW PGQARSLFGD
490 500 510 520 530 540
HDRFEQTYFS TFKGMYFSGD GARRDEDGYY WITGRVDDVL NISGHRLGTA EIESALVSHP
550 560 570 580 590 600
KIAEAAVVGT PHNIKGQAIY AYVTLNHGEE PSPELYTEVR NWVRKEIGPI ATPDILHWTD
610 620 630 640 650
SLPKTRSGKI MRRILRKIAS GDTNNLGDIS TLADPGVVEK LLEEKQTMSI S