Q7M938

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
KEGG Pathway
wsu:WS1218
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

245-363 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7M938

Entry ID Method Resolution Chain Position Source
AF-Q7M938-F1 Predicted AlphaFoldDB

No variants for Q7M938

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7M938

No associated diseases with Q7M938

3 regional properties for Q7M938

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 276 - 285 IPR020557
domain Fumarate lyase, N-terminal 7 - 301 IPR022761
domain Argininosuccinate lyase, C-terminal 365 - 432 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKLWAGRFL EASSELLERF NASLPFDKAL YFEDIKGSKA HAKMLAKQEI ITAKECEEIL
70 80 90 100 110 120
AGLEKVLGEI ERGEFVFKIA DEDIHMAIEA RLTELIGASG KKLHTARSRN DQVAVDFRMF
130 140 150 160 170 180
VLRKNEEIRA QILELMETIL EIASKHISTL MPGMTHLQHA QPVSFGFHMN AYACMFKRDV
190 200 210 220 230 240
ERLEDSHKRH NYCPLGSAAL AGTPYPTDRE FLAKELGFLA PTLNAMDSVS DRDFALDLLY
250 260 270 280 290 300
DIAMVMMHIS RLAEEMVLWS SYEFKFITLS DAYSTGSSIM PQKKNPDVPE LLRGKSGRVY
310 320 330 340 350 360
GNLLSLLTVM KGLPLAYNKD TQEDKEGVMD SVETAQISLA ILKEALKSAT INAKAMEEAC
370 380 390 400 410 420
KRGHLTATDL ADFLVRSCEV PFREAHHITG QVVAYAESKG KDISELSEAE ILGIDSRIKA
430 440 450 460
GVKEVLSLKN SMNARNSLGG TSSAQTKAQI KTLHTWLKKR LK