Q7M922

PR
Gene name
nhaA
Protein name
Na(+)/H(+) antiporter NhaA
Names
Sodium/proton antiporter NhaA
Species
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
KEGG Pathway
wsu:WS1251
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

249-327 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7M922

Entry ID Method Resolution Chain Position Source
AF-Q7M922-F1 Predicted AlphaFoldDB

No variants for Q7M922

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7M922

No associated diseases with Q7M922

2 regional properties for Q7M922

Type Name Position InterPro Accession
domain FeS cluster biogenesis 17 - 112 IPR000361
domain NIF system FeS cluster assembly, NifU, C-terminal 127 - 198 IPR001075

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
sodium ion transmembrane transporter activity Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
regulation of pH Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAENQDYASG NGGIKALLLN FIHSQSFSGI FLFFCAVVAM ISANSALSES YFHLWHTEIG
70 80 90 100 110 120
FFIGETFIGM SLHHWINDVL MSFFFLMVGL EIKRELLFGE LAGIKRAAFP AIAALGGMIV
130 140 150 160 170 180
PAIVYTLFNF GTDSAHGFGI PMATDIAFAL GVLLLLGDKV SLALKVFLVS LAVVDDLGAV
190 200 210 220 230 240
VVIAIFYTED LQTLWLLYSV VILGLLIGLN KMGVRSLFPY AILGVLLWIT VHNCGIHATI
250 260 270 280 290 300
AAVALAFTIP VKPKIESENF AQEAKELLER FLSHDKERAN LLLASEQVHS VELLSKHSKS
310 320 330 340 350 360
VQSPLVRLEH ALHPWSAYFI MPVFAFANAG VAISSNIHFD IDGVLPGIML GLIVGKPVGI
370 380 390 400 410 420
LGLTYLAEKM GIATRPEGVM WIDILGAGML AGIGFTMSIF ITNLAFTNPE ATDVAKIAIL
430 440 450
SASLFAGALG YFFISIRCRF KKKKEACCTI KS