Q7K237
Gene name |
C1GalTA (CG9520) |
Protein name |
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
Names |
Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, Core 1 beta1,3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1 |
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG9520 |
EC number |
2.4.1.122: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q7K237
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7Q4I | X-ray | 240 A | A/B | 73-388 | PDB |
| AF-Q7K237-F1 | Predicted | AlphaFoldDB |
No variants for Q7K237
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7K237 | |||||
No associated diseases with Q7K237
No regional properties for Q7K237
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q7K237 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.122 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-1,3-galactosyltransferase activity | Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage. |
| glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan. |
| metal ion binding | Binding to a metal ion. |
8 GO annotations of biological process
| Name | Definition |
|---|---|
| central nervous system morphogenesis | The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. |
| glycolipid biosynthetic process | The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). |
| muscle cell development | The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. |
| negative regulation of hematopoietic stem cell differentiation | Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. |
| neuromuscular junction development | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. |
| O-glycan processing, core 1 | The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc. |
| protein glycosylation | A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. |
| regulation of filopodium assembly | Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTANSLLGRS | ILNEGRSNKR | SFVSLIVGLI | VGFCLAELFV | YSTPERSEFM | PYDGHRHGDV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NDAHHSHDMM | EMSGPEQDVG | GHEHVHENST | IAERLYSEVR | VLCWIMTNPS | NHQKKARHVK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RTWGKRCNKL | IFMSSAKDDE | LDAVALPVGE | GRNNLWGKTK | EAYKYIYEHH | INDADWFLKA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DDDTYTIVEN | MRYMLYPYSP | ETPVYFGCKF | KPYVKQGYMS | GGAGYVLSRE | AVRRFVVEAL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PNPKLCKSDN | SGAEDVEIGK | CLQNVNVLAG | DSRDSNGRGR | FFPFVPEHHL | IPSHTDKKFW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YWQYIFYKTD | EGLDCCSDNA | ISFHYVSPNQ | MYVLDYLIYH | LRPYGIINTP | DALPNKLAVG |
| 370 | 380 | ||||
| ELMPEIKEQA | TESTSDGVSK | RSAETKTQ |