Q7JW12

PR
Gene name
CG11007
Protein name
Thioredoxin-related transmembrane protein 2 homolog
Names
Thioredoxin domain-containing protein 14 homolog
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG11007
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

187-271 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7JW12

Entry ID Method Resolution Chain Position Source
AF-Q7JW12-F1 Predicted AlphaFoldDB

No variants for Q7JW12

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7JW12

No associated diseases with Q7JW12

2 regional properties for Q7JW12

Type Name Position InterPro Accession
domain Cell division control protein 73, C-terminal 358 - 520 IPR031336
domain Paf1 complex subunit Cdc73, N-terminal domain 1 - 297 IPR032041

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

1 GO annotations of molecular function

Name Definition
disulfide oxidoreductase activity Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTWKKQMALL AKPYYWVNIL LAISYLLAKK TQFICTRLFI LAGEDEACDL DSREVEILFF
70 80 90 100 110 120
LLIVVMIRSR KTGSVTMINY LASSFLYTKV ANAILWAYAD FRYGLGFLLL CVLVGMVLPE
130 140 150 160 170 180
PSYRGPEHIT YFRNAQVFEE ELARDKRTSW LICFYTVWNP SCVNFAPVFA ELSAEYNTDH
190 200 210 220 230 240
LKFGKIDIGR FPDVAQKYRI SDSSFSRQLP TVILFQQGKE TDRRPCVDSK GKLQKFFFSS
250 260 270
DNVRATFGLN QLYKEAIERL PIAPKEAKKV Q