Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7CLU6

Entry ID Method Resolution Chain Position Source
AF-Q7CLU6-F1 Predicted AlphaFoldDB

No variants for Q7CLU6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7CLU6

No associated diseases with Q7CLU6

17 regional properties for Q7CLU6

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 318 - 460 IPR000722-1
domain RNA polymerase, alpha subunit 911 - 944 IPR000722-2
domain Hint domain C-terminal 871 - 917 IPR003586
domain Hint domain N-terminal 458 - 557 IPR003587
domain Intein DOD homing endonuclease 616 - 783 IPR004042
domain Homing endonuclease, LAGLIDADG 727 - 818 IPR004860
ptm Intein N-terminal splicing region 460 - 537 IPR006141
domain Intein 524 - 537 IPR006142-1
domain Intein 613 - 625 IPR006142-2
domain Intein 770 - 785 IPR006142-3
domain Intein 888 - 905 IPR006142-4
domain RNA polymerase, N-terminal 208 - 972 IPR006592
domain RNA polymerase Rpb1, domain 3 947 - 1110 IPR007066
domain RNA polymerase Rpb1, domain 1 8 - 316 IPR007080
domain RNA polymerase Rpb1, domain 5 1249 - 1325 IPR007081
domain RNA polymerase Rpb1, domain 4 1136 - 1242 IPR007083
domain Intein C-terminal splicing region 889 - 912 IPR030934

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
large ribosomal subunit The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).

2 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
ribosome assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTMEAKAILR TARISPQKAR LVADQVRGLS AERAVNLLKF SDKKAAHLIK KVVESAIANA
70 80 90 100 110
ENNQGADVDE LKVKTIMVDE GPSLKRFMAR AKGRGTRILK RTSHITVVVG AAK