Q7CJN8

PR
Gene name
trmJ (YPO2898, y1332, YP_2556)
Protein name
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ
Names
tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase
Species
Yersinia pestis
KEGG Pathway
ypm:YP_2556
EC number
2.1.1.200: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7CJN8

Entry ID Method Resolution Chain Position Source
AF-Q7CJN8-F1 Predicted AlphaFoldDB

No variants for Q7CJN8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7CJN8

No associated diseases with Q7CJN8

1 regional properties for Q7CJN8

Type Name Position InterPro Accession
domain tRNA/rRNA methyltransferase, SpoU type 5 - 154 IPR001537

Functions

Description
EC Number 2.1.1.200 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
tRNA (cytosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine.
tRNA (uracil-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil.

1 GO annotations of biological process

Name Definition
tRNA nucleoside ribose methylation The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLHNIRIVLV ETSHTGNMGS TARAMKTMGL TNLYLVNPLV KPDSQAIALS AGASDVIGKA
70 80 90 100 110 120
TIVDTLDEAL AGCSLVVGTS ARSRTLPWPM LEPRECGVRS AREAEHAPVA LVFGRERVGL
130 140 150 160 170 180
TNDELQKCHY HVAIPANPEY SSLNLAMAVQ ILAYEVRVAY LDRQQANAPV EEEEEAPYPL
190 200 210 220 230 240
VDDLERFYQH LEQVLSHSGF IRQAHPGQIM SKLRRLFTRA RPEAQELNIL RGMLTSIEKQ
250
DKYPQRGTGD TAGKSKD