Q7ADF8

PR
Gene name
hxpB
Protein name
Hexitol phosphatase B
Names
2-deoxyglucose-6-phosphate phosphatase, Mannitol-1-phosphatase, Sorbitol-6-phosphatase, Sugar-phosphatase
Species
Escherichia coli O157:H7
KEGG Pathway
ecs:ECs_2433
EC number
3.1.3.22: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

146-220 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7ADF8

Entry ID Method Resolution Chain Position Source
AF-Q7ADF8-F1 Predicted AlphaFoldDB

No variants for Q7ADF8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7ADF8

No associated diseases with Q7ADF8

2 regional properties for Q7ADF8

Type Name Position InterPro Accession
conserved_site Isocitrate/isopropylmalate dehydrogenase, conserved site 304 - 323 IPR019818
domain Isopropylmalate dehydrogenase-like domain 34 - 414 IPR024084

Functions

Description
EC Number 3.1.3.22 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

7 GO annotations of molecular function

Name Definition
2-deoxyglucose-6-phosphatase activity Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.
glucose-6-phosphatase activity Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.
mannitol-1-phosphatase activity Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate.
metal ion binding Binding to a metal ion.
sorbitol-6-phosphatase activity Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate.
sugar-phosphatase activity Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTPRQILAA IFDMDGLLID SEPLWDRAEL DVMASLGVDI SRRNELPDTL GLRIDMVVDL
70 80 90 100 110 120
WYARQPWNGP SRQEVVERVI ARAISLVEET RPLLPGVREA VALCKEQGLL VGLASASPLH
130 140 150 160 170 180
MLEKVLTMFD LRDSFDALAS AEKLPYSKPH PQVYLDCAAK LGVDPLTCVA LEDSVNGMIA
190 200 210 220
SKAARMRSIV VPAPEAQNDP RFVLANVKLS SLTELTAKDL LG