Q7A7X6

PR
Gene name
pflB (SA0218)
Protein name
Formate acetyltransferase
Names
Pyruvate formate-lyase
Species
Staphylococcus aureus (strain N315)
KEGG Pathway
sau:SA0218
EC number
2.3.1.54: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-145 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7A7X6

Entry ID Method Resolution Chain Position Source
AF-Q7A7X6-F1 Predicted AlphaFoldDB

No variants for Q7A7X6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7A7X6

No associated diseases with Q7A7X6

3 regional properties for Q7A7X6

Type Name Position InterPro Accession
domain Glycine radical domain 624 - 749 IPR001150
domain Pyruvate formate lyase domain 3 - 619 IPR004184
conserved_site Formate C-acetyltransferase glycine radical, conserved site 719 - 727 IPR019777

Functions

Description
EC Number 2.3.1.54 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
formate C-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.

1 GO annotations of biological process

Name Definition
glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLETNKNHAT AWQGFKNGRW NRHVDVREFI QLNYTLYEGN DSFLAGPTEA TSKLWEQVMQ
70 80 90 100 110 120
LSKEERERGG MWDMDTKVAS TITSHDAGYL DKDLETIVGV QTEKPFKRSM QPFGGIRMAK
130 140 150 160 170 180
AACEAYGYEL DEETEKIFTD YRKTHNQGVF DAYSREMLNC RKAGVITGLP DAYGRGRIIG
190 200 210 220 230 240
DYRRVALYGV DFLMEEKMHD FNTMSTEMSE DVIRLREELS EQYRALKELK ELGQKYGFDL
250 260 270 280 290 300
SRPAENFKEA VQWLYLAYLA AIKEQNGAAM SLGRTSTFLD IYAERDLKAG VITESEVQEI
310 320 330 340 350 360
IDHFIMKLRI VKFARTPDYN ELFSGDPTWV TESIGGVGID GRPLVTKNSF RFLHSLDNLG
370 380 390 400 410 420
PAPEPNLTVL WSVRLPDNFK TYCAKMSIKT SSIQYENDDI MRESYGDDYG IACCVSAMTI
430 440 450 460 470 480
GKQMQFFGAR ANLAKTLLYA INGGKDEKSG AQVGPNFEGI NSEVLEYDEV FKKFDQMMDW
490 500 510 520 530 540
LAGVYINSLN VIHYMHDKYS YERIEMALHD TEIVRTMATG IAGLSVAADS LSAIKYAQVK
550 560 570 580 590 600
PIRNEEGLVV DFEIEGDFPK YGNNDDRVDD IAVDLVERFM TKLRSHKTYR DSEHTMSVLT
610 620 630 640 650 660
ITSNVVYGKK TGNTPDGRKA GEPFAPGANP MHGRDQKGAL SSLSSVAKIP YDCCKDGISN
670 680 690 700 710 720
TFSIVPKSLG KEPEDQNRNL TSMLDGYAMQ CGHHLNINVF NRETLIDAME HPEEYPQLTI
730 740
RVSGYAVNFI KLTREQQLDV ISRTFHESM