Q7A3K7

PR
Gene name
pgcA (SA2279)
Protein name
Phosphoglucomutase
Names
PGM, Alpha-phosphoglucomutase, Glucose phosphomutase
Species
Staphylococcus aureus (strain N315)
KEGG Pathway
sau:SA2279
EC number
5.4.2.2: Phosphotransferases (phosphomutases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-75 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7A3K7

Entry ID Method Resolution Chain Position Source
AF-Q7A3K7-F1 Predicted AlphaFoldDB

No variants for Q7A3K7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7A3K7

No associated diseases with Q7A3K7

5 regional properties for Q7A3K7

Type Name Position InterPro Accession
domain Alpha-D-phosphohexomutase, C-terminal 472 - 532 IPR005843
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain I 42 - 169 IPR005844
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain II 204 - 305 IPR005845
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain III 316 - 436 IPR005846
conserved_site Alpha-D-phosphohexomutase, conserved site 137 - 146 IPR016066

Functions

Description
EC Number 5.4.2.2 Phosphotransferases (phosphomutases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoglucomutase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

2 GO annotations of biological process

Name Definition
enterobacterial common antigen biosynthetic process The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKGCLATMDK ELWIERANDS LVKHFYEQQS DIEQREGFES KLTFGTAGIR GKFGLGEGRL
70 80 90 100 110 120
NKFTIEKLAL GLARYLNAQT NSPTIVIHYD IRHLSTEFAQ IIANVLANHQ ITVYLPDTYK
130 140 150 160 170 180
TTPELSFAVR NLNTTAGIMI TASHNPKDYN GIKVYGSDGA QLSTDASELA SRYIEEVGDP
190 200 210 220 230 240
LQIDIPISKQ NTSYIKPFPK SVTDDYMKHI QNMIGYIPKS DLQVVFTSLH GTSVPIVPEL
250 260 270 280 290 300
LKSLNFNQFN LVDAQCKPDP NFSSVQSANP EDHRAFDQAV ELANKSHADL LISTDPDADR
310 320 330 340 350 360
LGIAERDAHG HITYFNGNQI GALLLNYRIQ QTSQLRHRLM IQSIVSSELT KSLARYNNVK
370 380 390 400 410 420
YKEVLTGFKF IAQEIRQLDD HQNMIFAFEE SYGFLSEPFV RDKDAVQIVP LIIKYASELK
430 440 450 460 470 480
LYGKTLKDEL EQIYQTVGRH EDTLFSHTLE GLEGKKKIES IMTHFRSNPP QEIQGLKVKA
490 500 510 520 530 540
IEDYLTSEVY HLDKDTTSQI NSSKSNVIRV LFDEGFIALR PSGTEPKIKL YVSLKCPDFD
550
DVAQKINAMI FS