Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7A3F2

Entry ID Method Resolution Chain Position Source
AF-Q7A3F2-F1 Predicted AlphaFoldDB

No variants for Q7A3F2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7A3F2

No associated diseases with Q7A3F2

5 regional properties for Q7A3F2

Type Name Position InterPro Accession
domain Ferrous iron transport protein B, C-terminal 454 - 506 IPR011640
domain Nucleoside transporter/FeoB GTPase, Gate domain 350 - 444 IPR011642-1
domain Nucleoside transporter/FeoB GTPase, Gate domain 511 - 635 IPR011642-2
domain FeoB-type guanine nucleotide-binding (G) domain 1 - 161 IPR030389
domain FeoB, cytosolic helical domain 170 - 259 IPR041069

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ferrous iron transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
GTP binding Binding to GTP, guanosine triphosphate.

1 GO annotations of biological process

Name Definition
iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MENYCILGNP NVGKTSLFNA LTGSYEYIGN WSGVTVEKKV GKLKENVGQL IDLPGTYDLS
70 80 90 100 110 120
PISKDETVVT DYLLNDSFSG IINIVDASQL KRNVQLTVQL LELNQPIYIG LNMIDVATKR
130 140 150 160 170 180
GIKIDYHKLM KKLKTPIFPV VARTGKGTKY LLGEIKHLGE GYQPHFKINY GEKIEETIKN
190 200 210 220 230 240
MCQIIMTETS HDKYQARFIA IQFLLNNMQI ANELNSEVVN KLSSLRDQVA EQVGAVSVRR
250 260 270 280 290 300
EMERIRNHYI ETLLQDVVTY PDEDKQYFSS RIDKILTHKY IGMPIFLAIM WLIFQTTFTW
310 320 330 340 350 360
IGTPLSDQLD AFIGGTFTDS VKTIMNYLGV IPFLQDLITD GIIAGVGSVL VFVPQIVVLF
370 380 390 400 410 420
FFISLLEDSG YMARIAVLMD RIMESFGLSG KSFIPMIIGF GCNVPSIMAA RSIENEKERL
430 440 450 460 470 480
TTILIAPFMS CSARLPVYAL FVGIFFKENQ SLVVLSLYVL GIIMAFLVST VLTKTILKND
490 500 510 520 530 540
NAIFIVELPT YRVPSIKTLW RSTWEKAKGF VRKAGTFIFG GSVVIWLLSY VGPHGINVNI
550 560 570 580 590 600
NQSFLHMVGS FFGMLVQPLG FGTWQAGATL VPGFLAKEVI VSSMAIIYSS GDAGLVNVIQ
610 620 630 640 650 660
NQFTPLSAYA FMIFILLYIP CVSTVAAIRK ETYSWKWTAL AVAYPLVTAY VLTFIFYQVG
HLFV