Q7A1I3
Gene name |
ltaS (MW0681) |
Protein name |
Lipoteichoic acid synthase |
Names |
|
Species |
Staphylococcus aureus (strain MW2) |
KEGG Pathway |
sam:MW0681 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
5 structures for Q7A1I3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2W5Q | X-ray | 120 A | A | 218-641 | PDB |
| 2W5R | X-ray | 170 A | A | 218-641 | PDB |
| 2W5S | X-ray | 210 A | A | 218-641 | PDB |
| 2W5T | X-ray | 160 A | A | 218-641 | PDB |
| AF-Q7A1I3-F1 | Predicted | AlphaFoldDB |
No variants for Q7A1I3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7A1I3 | |||||
No associated diseases with Q7A1I3
1 regional properties for Q7A1I3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Sulfatase, N-terminal | 247 - 539 | IPR000917 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| sulfuric ester hydrolase activity | Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| lipoteichoic acid biosynthetic process | The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSQKKKISL | FAFFLLTVIT | ITLKTYFSYY | VDFSLGVKGL | VQNLILLMNP | YSLVALVLSV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FLFFKGKKAF | WFMFIGGFLL | TFLLYANVVY | FRFFSDFLTF | STLNQVGNVE | SMGGAVSASF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KWYDFVYFID | TLVYLFILIF | KTKWLDTKAF | SKKFVPVVMA | ASVALFFLNL | AFAETDRPEL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTRTFDHKYL | VKYLGPYNFT | VYDGVKTIEN | NQQKALASED | DLTKVLNYTK | QRQTEPNPEY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YGVAKKKNII | KIHLESFQTF | LINKKVNGKE | VTPFLNKLSS | GKEQFTYFPN | FFHQTGQGKT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SDSEFTMDNS | LYGLPQGSAF | SLKGDNTYQS | LPAILDQKQG | YKSDVMHGDY | KTFWNRDQVY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KHFGIDKFYD | ATYYDMSDKN | VVNLGLKDKI | FFKDSANYQA | KMKSPFYSHL | ITLTNHYPFT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LDEKDATIEK | SNTGDATVDG | YIQTARYLDE | ALEEYINDLK | KKGLYDNSVI | MIYGDHYGIS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ENHNNAMEKL | LGEKITPAKF | TDLNRTGFWI | KIPGKSGGIN | NEYAGQVDVM | PTILHLAGID |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TKNYLMFGTD | LFSKGHNQVV | PFRNGDFITK | DYKYVNGKIY | SNKNNELITT | QPADFEKNKK |
| 610 | 620 | 630 | 640 | ||
| QVEKDLEMSD | NVLNGDLFRF | YKNPDFKKVN | PSKYKYETGP | KANSKK |