Q791T5
Gene name |
Mtch1 |
Protein name |
Mitochondrial carrier homolog 1 |
Names |
Mitochondrial carrier-like protein 1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:56462 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q791T5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q791T5-F1 | Predicted | AlphaFoldDB |
15 variants for Q791T5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389416567 | 133 | F>C | No | EVA | |
| rs3389450149 | 151 | G>V | No | EVA | |
| rs3389447329 | 168 | S>C | No | EVA | |
| rs3389447283 | 219 | S>L | No | EVA | |
| rs3389452029 | 223 | M>I | No | EVA | |
| rs3411699757 | 236 | V>M | No | EVA | |
| rs3389416590 | 246 | E>D | No | EVA | |
| rs3389362132 | 249 | L>E | No | EVA | |
| rs3389428304 | 250 | L>V | No | EVA | |
| rs3389443775 | 333 | D>E | No | EVA | |
| rs3389452008 | 338 | N>K | No | EVA | |
| rs217585564 | 343 | R>Q | No | EVA | |
| rs13473933 | 355 | S>Y | No | EVA | |
| rs3389408096 | 362 | Y>C | No | EVA | |
| rs3389441191 | 381 | S>T | No | EVA |
No associated diseases with Q791T5
2 regional properties for Q791T5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Mitochondrial substrate/solute carrier | 81 - 176 | IPR018108-1 |
| repeat | Mitochondrial substrate/solute carrier | 192 - 280 | IPR018108-2 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| activation of cysteine-type endopeptidase activity involved in apoptotic process | Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. |
| apoptotic process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| positive regulation of apoptotic process | Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9NZJ7 | MTCH1 | Mitochondrial carrier homolog 1 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGASDPEVAP | WAPGGAAGMA | GAGAGAGARG | GAPAGVEARA | RDPPPAHRAH | PRHPRPAAQP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SARRMDGGPG | APGSGDNAPT | TEALFVALGA | GVTALSHPLL | YVKLLIQVGH | EPMPPTLGTN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VLGRKVLYLP | SFFTYAKYIV | QVDGKIGLFR | GLSPRLMSNA | LSTVTRGSMK | KVFPPDEMEQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VSNKDDMKTS | LKKVVKETSY | EMMMQCVSRM | LAHPLHVISM | RCMVQFVGRE | AKYSGVLSSI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GKIFKEEGLL | GFFVGLIPHL | LGDVVFLWGC | NLLAHFINAY | LVDDSVSDTP | GGLGNDQNPG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SQFSQALAIR | SYTKFVMGIA | VSMLTYPFLL | VGDLMAVNNC | GLRAGLPPYS | PVFKSWIHCW |
| 370 | 380 | ||||
| KYLSVQGQLF | RGSSLLFRRV | SSGSCFALE |