Q76IQ2

PR
Gene name
PMI1 (PMI40, CAGL0J02244g)
Protein name
Mannose-6-phosphate isomerase
Names
SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, Phosphohexomutase, Phosphomannose isomerase, PMI
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0J02244g
EC number
5.3.1.8: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

32-161 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q76IQ2

Entry ID Method Resolution Chain Position Source
AF-Q76IQ2-F1 Predicted AlphaFoldDB

No variants for Q76IQ2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q76IQ2

No associated diseases with Q76IQ2

5 regional properties for Q76IQ2

Type Name Position InterPro Accession
conserved_site Phosphomannose isomerase, type I, conserved site 129 - 137 IPR018050-1
conserved_site Phosphomannose isomerase, type I, conserved site 282 - 307 IPR018050-2
domain Phosphomannose isomerase type I, C-terminal domain 346 - 393 IPR046456
domain Phosphomannose isomerase type I, catalytic domain 7 - 154 IPR046457
domain Phosphomannose isomerase type I, helical insertion domain 171 - 263 IPR046458

Functions

Description
EC Number 5.3.1.8 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
mannose-6-phosphate isomerase activity Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
cell wall mannoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
GDP-mannose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSDRFFRLD AGYQQYDWGK IGSSSAVAKF AAHSDPSVKI DETKPYAELW MGTHSKLPSV
70 80 90 100 110 120
NHETKATLND ILAKNSQELI GEDVINKFKS TNELPFLFKV LSIEKVLSIQ AHPDKELGKK
130 140 150 160 170 180
LHMEDPKNYP DDNHKPEMAV AITEFEGFCG FKPLEEIADE LETIPEFRDV VGDEVANEFI
190 200 210 220 230 240
QNYKTGVENS SSACANNKKL LQKVFEKVMT APCDILEKNA DGMAKRANEN PSSFKSSDLP
250 260 270 280 290 300
ELVVRLNRQF PKDVGLFCGC LMLNHCKLQP GQALFLEAKD PHAYICGDII ECMAASDNVV
310 320 330 340 350 360
RAGFTPKFKD VKNLVEMLTY RYDPVEKQVM SAEEFPRAGG DGATIMYNPP IAEFSVLETT
370 380 390 400 410 420
FKNKTGKATV EGLKGPSIVI TTAGEGYISA DGQKLKAEPG FVFFIGANVP VELETTDKDF
TTYRAFVEA