Q75JD4
Gene name |
DDB_G0271676 |
Protein name |
SH3 and F-BAR domain-containing protein DDB_G0271676 |
Names |
|
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0271676 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q75JD4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q75JD4-F1 | Predicted | AlphaFoldDB |
No variants for Q75JD4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q75JD4 | |||||
No associated diseases with Q75JD4
4 regional properties for Q75JD4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | FCH domain | 5 - 93 | IPR001060 |
| domain | SH3 domain | 406 - 468 | IPR001452-1 |
| domain | SH3 domain | 476 - 533 | IPR001452-2 |
| domain | F-BAR domain | 5 - 258 | IPR031160 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| vesicle | Any small, fluid-filled, spherical organelle enclosed by membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
| phosphatidylinositol binding | Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament polymerization | Assembly of actin filaments by the addition of actin monomers to a filament. |
| chemotaxis to cAMP | The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP. |
| clathrin-dependent endocytosis | An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles. |
| vesicle organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAQRQFSED | LWDKFESVVK | KVDNGKIFTQ | QLSKFLSKQQ | QIESAYAKSL | VKLCKDKSFA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PEVEMGTLRD | SFQCYREQLE | LIGALHEEFS | NRLEKLVTIG | IDGYLEESRK | QRKALIANGE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KCTKDLKTAE | SNESKAKQNY | EKLKRKQEEA | NEDLSKQPPG | AKEQKARKTL | ESATKAADKG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DNEYRESVKC | LQQNQQKFYH | EEMPRILDDL | QRFEVERIDK | SKDWLMEVIT | QNELVPPAVI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IHNENIKKGI | ESIDRERDLQ | NYILVTMSGA | QKPPEAQYEP | YQSGGGFAIV | NSSSNSNLNI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SRKSGELNGG | GSIQNGASII | SSPQQPQYQN | IDHQTPPQPN | IIIQQHQQSN | NNNNTNNNSN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VMTTPPPPQP | QPQQQQLPQP | TQLNNPPQPP | ISLSKNDSSN | SINSNSNGEI | VRALYDYNAT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EENEISFKAN | ALIKVVLRDE | SGWWQGMVIG | ESDRIGVFPS | NFISDSSDSS | KKRVDVAGRK |
| 490 | 500 | 510 | 520 | 530 | |
| CKVLYDYRTD | CEGELNIKEG | EILTIEYEDE | GWFFGSNESN | VSARFPSNYV | QVI |