Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q75F81

Entry ID Method Resolution Chain Position Source
AF-Q75F81-F1 Predicted AlphaFoldDB

No variants for Q75F81

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q75F81

No associated diseases with Q75F81

4 regional properties for Q75F81

Type Name Position InterPro Accession
domain EF-hand domain 39 - 110 IPR002048-1
domain EF-hand domain 112 - 183 IPR002048-2
binding_site EF-Hand 1, calcium-binding site 52 - 64 IPR018247-1
binding_site EF-Hand 1, calcium-binding site 88 - 100 IPR018247-2

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
signaling receptor activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.

1 GO annotations of biological process

Name Definition
cellular zinc ion homeostasis Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSHPNTHMPR THAVHGRAAP QRRGCRTSVE KTDQSGHSRS SLAESAMEQA QLRSRGEAGG
70 80 90 100 110 120
GRSVLCASGE PGSAHKWAGA VTCSGAEEQP LHWAESRARG LARHLHYWEL PYAWRENRYI
130 140 150 160 170 180
IYGHRFYHSH RKSLLSVLNA YGWHNETINI WSHLVGAAVL AYLLCWGWPR SDVYRAAQVP
190 200 210 220 230 240
RLAKWAIGAF LACGVKCMAS SVAWHTFNGT CHLKLRSRFV CVDYTGITLL VTASVVTTVA
250 260 270 280 290 300
VTLYGLSRPL MYAYMVASIG LGTAAGVMNW SPHFDRPEAR PLRIAVYVGL AALGLVSFVH
310 320 330 340 350 360
VWMQVRWASA HLMAPLVYKS LVWYGIGVVF YATLVPERWR SDVTLDCCSG PVHEAACRQF
370 380 390 400 410
RDLPPVARKD RQFWSLWWVD YFCHSHFLWH VFVVLGVVGH YRAVLQMSRI VWLDAGRAF