Q75EV6

PR
Gene name
TEF3 (AAL028W)
Protein name
Elongation factor 3
Names
EF-3
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_AAL028W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

31-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q75EV6

Entry ID Method Resolution Chain Position Source
AF-Q75EV6-F1 Predicted AlphaFoldDB

No variants for Q75EV6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q75EV6

No associated diseases with Q75EV6

9 regional properties for Q75EV6

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 426 - 641 IPR003439-1
domain ABC transporter-like, ATP-binding domain 667 - 993 IPR003439-2
domain AAA+ ATPase domain 455 - 616 IPR003593-1
domain AAA+ ATPase domain 693 - 969 IPR003593-2
domain Elongation Factor 3, ABC2 domain, chromodomain-like insertion 794 - 861 IPR015688
conserved_site ABC transporter-like, conserved site 544 - 558 IPR017871-1
conserved_site ABC transporter-like, conserved site 897 - 911 IPR017871-2
repeat HEAT, type 2 171 - 209 IPR021133
domain Elongation factor 3, four helical bundle domain 336 - 411 IPR040533

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic ribosome A ribosome located in the cytosol.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

2 GO annotations of biological process

Name Definition
cellular response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
cytoplasmic translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDSAQSIKV LGELFEKLSV ATAENREATA TEIASFLNGN IIEHDVPEEF FKNLTKAVKD
70 80 90 100 110 120
KKTAAAALET IAHIANENNL SPSVEPYIVD LVPEVCVKTG DKDKDVQSIA SETLLAIVKA
130 140 150 160 170 180
IDPVAIKVIL PHLTKSLVTT NKWQEKVSVL AAISALVDAA KTQVALRMPE LIPVLSEAMW
190 200 210 220 230 240
DTKKEVKHAA TATMTKATET VDNKDIERFI PELIQCIADP SQVSETVHLL GATTFVAEVT
250 260 270 280 290 300
PATLSIMVPL LNRGLAERET SIKRKAAVII DNMCKLVEDP QVVAPFLEKL LPGLKNNFAT
310 320 330 340 350 360
IADPEAREVT LRGLKTLRRV GNVSDDDTLP EVSHAGDIVT TRGVLDELTK DTPIAPRFAP
370 380 390 400 410 420
VVNYIAAIAA DLIDERIIDQ QAWFTHVTPY MTVFFHEKQS KEIIDDFRKR AVDNIPVGPN
430 440 450 460 470 480
FDDEEDEGED LCNCEFSLAY GAKILLNKTQ LRLKRARRYG LCGPNGAGKS TLMRAIANGQ
490 500 510 520 530 540
VDGFPTQDEC RTVYVEHDID GTQADTSVLD FVFQGDVGTR EVITEKLREF GFSDEMIAMP
550 560 570 580 590 600
IMSLSGGWKM KLALARAVLK NADILLLDEP TNHLDTVNVA WLVNYLNTCG ITSIIVSHDS
610 620 630 640 650 660
GFLDNVCQYI IHYEGLKLRK YKGNLSEFVK KCPTAKSYYE LGASDLEFKF PEPGFLEGVK
670 680 690 700 710 720
TKQKAIVKVS NMSFQYPGTS KPQIADINFQ CSLSSRIAVI GPNGAGKSTL INVLTGELLP
730 740 750 760 770 780
TTGEVYTHEN CRIAYIKQHA FAHIENHLDK TPSEYIQWRF QTGEDRETMD RANRQINESD
790 800 810 820 830 840
AESMNKIFKI DGTPRRIAGI HSRRKFKNTY EYECSFLLGE NIGMKSERWV PMMSVDNAWL
850 860 870 880 890 900
PRGELIESHS KMVAEVDMKE ALASGQFRPL TRKEIEEHCA MLGLEAELVS HSRIRGLSGG
910 920 930 940 950 960
QKVKLVLAAC TWQRPHLIVL DEPTNYLDRD SLGALSKALK AFEGGVIIIT HSAEFTKDLT
970 980 990 1000 1010 1020
EEVWAVKDGI MTPSGHNWVS GQGSGPRLEK KEDEGDKFDA MGNKIATGNK KKKLSSAELR
1030 1040
KKKKERMKKK KELGDAYVSS DDEF