Q75DC6

PR
Gene name
CSM3 (ABR100W)
Protein name
Chromosome segregation in meiosis protein 3
Names
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_ABR100W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q75DC6

Entry ID Method Resolution Chain Position Source
AF-Q75DC6-F1 Predicted AlphaFoldDB

No variants for Q75DC6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q75DC6

No associated diseases with Q75DC6

1 regional properties for Q75DC6

Type Name Position InterPro Accession
domain Chromosome segregation in meiosis protein 3 44 - 127 IPR012923

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
replication fork protection complex A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

7 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
DNA replication checkpoint signaling A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
establishment of mitotic sister chromatid cohesion The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
maintenance of DNA repeat elements Any process involved in sustaining the fidelity and copy number of DNA repeat elements.
meiotic chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
replication fork arrest Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.
replication fork protection Any process that prevents the collapse of stalled replication forks.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSVGPLEDE AAGTELGGSP ADPATLTEID PSAIQVRKTR TVVKLDCERL VSKKGLPYLL
70 80 90 100 110 120
KNAPKHARIS KRRDTYGNLC HVLQFYQLWA HELYPKAKFK DFVALCDRLG KTDRQLRAYR
130 140 150 160 170 180
MQLIREELGL AAEGLDPPPQ PLREHTGAGG SQPAGSVAQD TNTNADLSDD DLLYTTSRAA
190 200 210 220 230
AASSTANPVP RSETPAALAG VDEAELLAQL AEMQRAAEED VHESEDDEQL ALMREMDEFM