Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q75CC3

Entry ID Method Resolution Chain Position Source
AF-Q75CC3-F1 Predicted AlphaFoldDB

No variants for Q75CC3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q75CC3

No associated diseases with Q75CC3

3 regional properties for Q75CC3

Type Name Position InterPro Accession
domain Phox homology 138 - 260 IPR001683
domain SNX8/Mvp1, PX domain 143 - 256 IPR035704
domain Sorting nexin 8/Mvp1, BAR domain 271 - 521 IPR045734

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endosome A vacuole to which materials ingested by endocytosis are delivered.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.
phosphatidylinositol-3-phosphate binding Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.

3 GO annotations of biological process

Name Definition
plasma membrane tubulation A membrane tubulation process occurring in a plasma membrane.
protein targeting to vacuole The process of directing proteins towards the vacuole, usually using signals contained within the protein.
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMDLDSQELW GRGPSMESPN NAWASVQRTP ADSARTQQIV SPVVRQAESL GSLTLTDSSL
70 80 90 100 110 120
SAEVKETMRN NYNERKMYEP GTPALEQTVW GAPPSQLDAS ISGLDTSMAP VASQSSMCDE
130 140 150 160 170 180
LHSEDLENWM NSRRKTYNPL AKNIVVVEEI PEREGILFKH TNYLVKHLVV LPNTNPSSNQ
190 200 210 220 230 240
TVIRRYSDFN WLQEVLLKKY PFRMIPELPP KKIGAQNADP IFLARRRKGL CRFINLVIMH
250 260 270 280 290 300
PVLKQDDLVL TFLTVPTDLG SWRKQANYDT TEEFTDQKID KAFISLWHKE LSNQWNKADA
310 320 330 340 350 360
KIDELLESWI KTSVLVERYE RRMRQVSEER RLLGRVIEEF ADNSVTLYPL EEGTIHDINS
370 380 390 400 410 420
HISTISKHLN SLADTSKKER QEVEEHLSVK FKTFIDIIIA LKGVFDRYKI MAGNNIAHLQ
430 440 450 460 470 480
RRVEINMDKL QSMESNPDVK GAEYDKLRQT IQRDKRTIAE QLNRSWLIRK CILEEFVIFQ
490 500 510 520
ETQFCITHVF QEWAKMHVKY ANETTESWEK VYANLQDMPL SRS