Q75BY0
Gene name |
DGA1 (ACR140C) |
Protein name |
Diacylglycerol O-acyltransferase 1 |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_ACR140C |
EC number |
2.3.1.20: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q75BY0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q75BY0-F1 | Predicted | AlphaFoldDB |
No variants for Q75BY0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q75BY0 | |||||
No associated diseases with Q75BY0
No regional properties for Q75BY0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q75BY0 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.20 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cortical endoplasmic reticulum | A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| lipid droplet | An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. |
| perinuclear endoplasmic reticulum | The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2-acylglycerol O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol. |
| diacylglycerol O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular triglyceride homeostasis | Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment. |
| ceramide metabolic process | The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. |
| glycerol metabolic process | The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
| lipid droplet formation | A process that results in the assembly, arrangement of constituent parts of a lipid droplet. |
| lipid metabolic process | The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
| triglyceride biosynthetic process | The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQDSMDDSLR | EAEGRQDDSE | VSSGTTLGSS | TPEDSGVTAK | LRKKYQMASA | LLRRELEELS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VYDAKTAGVS | GRSSGSGSGG | LALLGGRFHV | APLRIPARRR | LQTLVVAWHT | SSFIYMTVLV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LFLAANPLMW | WFMVPYMVYY | VWNRSPANGG | VVRRYSPRLR | SLALWRYYCE | YYPISLHKSE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DLAPTFVPDP | RGAEPREWKL | RLWLWPTRVE | LLNLTLQWTR | ARPQVATGPR | YIFGYHPHGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GALGAFGAIA | TEGCNWSKVF | AGIPACLCTL | VNQFQIPIYR | DYLLGLGCTS | VARKNVLKVL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EQNYSVCIVV | GGAQEALLSR | VGSTELVLNK | RKGFIKLALE | TGNVNLVPIY | AFGETDCFNV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LDTGNESYLR | KFQLWIKKTY | GFTIPFFFAR | GVFNYDFGFL | PFRNPINVVV | GKPVYVDKRR |
| 430 | 440 | 450 | 460 | ||
| TNPTMEEIDH | YHDLYVQELR | NVFDKNKHKF | GYAGKELKIV | E |