Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q75BS7

Entry ID Method Resolution Chain Position Source
AF-Q75BS7-F1 Predicted AlphaFoldDB

No variants for Q75BS7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q75BS7

No associated diseases with Q75BS7

6 regional properties for Q75BS7

Type Name Position InterPro Accession
repeat WD40 repeat 177 - 215 IPR001680-1
repeat WD40 repeat 228 - 268 IPR001680-2
repeat WD40 repeat 320 - 362 IPR001680-3
repeat WD40 repeat 378 - 416 IPR001680-4
repeat WD40 repeat 470 - 508 IPR001680-5
conserved_site WD40 repeat, conserved site 347 - 361 IPR019775

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nuclear periphery The portion of the nuclear lumen proximal to the inner nuclear membrane.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
regulation of DNA damage checkpoint Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTANSEFNKR RLENIKRNNE LLKKLNLAGI PARIRSEAGI EDHRKASGGA VKKKQGKAPV
70 80 90 100 110 120
KREAKPAPIP TRRSRRLRGE AADVEGEAGA GSDTAQNVKQ EEEWKELKEA RVVGDIKLSD
130 140 150 160 170 180
LIKSEDDGEL LEKFRRYADK SFSGGDFFEE LQRHQKPNPE VQRLREEMRL QQYDVFDPKE
190 200 210 220 230 240
LAIVHERVTA LCFHPSQEKK LIVGGDTAGT VGLWNVADEN PDPEHPDSVP DITRFKLFSR
250 260 270 280 290 300
NVSKIEVFPT DSSKILAASY DGALRSIDMQ SLKSDELLHF QNEHGDTLGI SDCQFSYDSP
310 320 330 340 350 360
NVVMLTTLGG EFAQRDLRTK PDTMNIMRLS DKKIGCMAID PSRPYSVATA SLDRTLRIWD
370 380 390 400 410 420
LRKTVAKPDW SQYEDYASHE VVSTYNSRLS VSAVSYAPID HTLVCNGYDN TVRLFNARAD
430 440 450 460 470 480
LPSELQPDFT IQHNCKSGRW VSVLKARFKL NMDVFAIANM KRAIDIYTSR GEQLSHLETS
490 500 510
TVPAVVSWHP MQNWIVGGNN SGKVFLFTDA PQE