Q759R3

PR
Gene name
ALG8 (ADR210C)
Protein name
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Names
Asparagine-linked glycosylation protein 8, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_ADR210C
EC number
2.4.1.265: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q759R3

Entry ID Method Resolution Chain Position Source
AF-Q759R3-F1 Predicted AlphaFoldDB

No variants for Q759R3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q759R3

No associated diseases with Q759R3

1 regional properties for Q759R3

Type Name Position InterPro Accession
domain Aminoglycoside phosphotransferase 144 - 438 IPR002575

Functions

Description
EC Number 2.4.1.265 Hexosyltransferases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.

2 GO annotations of biological process

Name Definition
oligosaccharide-lipid intermediate biosynthetic process The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation.
protein N-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKRSEKTEG ANKSGRRRGP GSDAEGAEDS GTRRYSLWNF WVASTALKLL LMPGYYSTDF
70 80 90 100 110 120
EVHRNWLAVT HRLPLREWYV DATSQWTLDY PPLFAWFEWA LSQVVPGAVR RDGCLELVAE
130 140 150 160 170 180
GRYGWPTVVF QRLTVIASEV LLYVVLQVYV NRSAAQERTV NFVVATSVAL SPAFLLVDHI
190 200 210 220 230 240
HFQYNGFLFA VLVASIVAAR ERRYVLCGAL FTVALCLKHI FLYLAPAYFV FLLRAYVLDL
250 260 270 280 290 300
GEFRFRSYRD LVFAVRWGNL CRLGGVVLAI MAVTFAPFAG VMPQLMARLF PFSRGLTHAY
310 320 330 340 350 360
WAPNFWAIYS FVDKVLTFLM LRVPYVYKLA TSLVQPPLIP ASIDEIRARM AAGNHGTRGL
370 380 390 400 410 420
VQDVSFVILP QIQPKLTFLL TLFYQVLAVL PVLFDPSFKR FIGSLSLCGF SAFLFGWHVH
430 440 450 460 470 480
EKAIMLVIVP FSFLVSFDQR LLTPFRLLTA SGYVSLFPLL YSSSSFVIKV LYTLIWCIVY
490 500 510 520 530 540
HSALKRTVPA SASVQRRVFF FDRLAAVYVM LLLPMVLGVK YLELLEGKFE ALEKYQFLGL
550 560
MCYSIYCAIG VCTSWMGLSW LYNFDEPLWV