Q759H4

PR
Gene name
PEX3 (ADR296C)
Protein name
Peroxisomal biogenesis factor 3
Names
Peroxin-3
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_ADR296C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

67-153 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q759H4

Entry ID Method Resolution Chain Position Source
AF-Q759H4-F1 Predicted AlphaFoldDB

No variants for Q759H4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q759H4

No associated diseases with Q759H4

No regional properties for Q759H4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q759H4

Functions

Description
EC Number
Subcellular Localization
  • Peroxisome membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
integral component of peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
protein-macromolecule adaptor activity The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.

3 GO annotations of biological process

Name Definition
ER-dependent peroxisome organization A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.
peroxisome inheritance The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.
protein import into peroxisome membrane The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARTGLQRHR GKLLGTGAVL GGLVVAGVVA AVAAKRWVRR QQQRLSEQHY VREQIKRRFT
70 80 90 100 110 120
QTQQDALYTM YELVPVLALV LGKELDVEEL VETLKGKKLK RAGEDDEQGS GGHASAGEGS
130 140 150 160 170 180
VSSTVARSKA ELWQELKMRS AVKLLAVVYT TCMLLLLTRL QLNILARREY LETAIRVAKG
190 200 210 220 230 240
EEATRRDAAG WLGAVWEYGA AALGALGPRP AVTAVEPVDQ HEETRYVNEQ AFLSLSWWLL
250 260 270 280 290 300
NRGWLQFKPL IERQVEQQFG TLSPRDTLSM EQFSARLSNT IHAVNRELFD SDSRALLLRA
310 320 330 340 350 360
LLPDATEELH VLQQTLDEGS LRVIERDDSM LRELLQETCR CAESTASLIV LESLVNESFQ
370 380 390 400 410 420
FVMQQLETKV TKKLRKPATD APEADGAADA PSQKFQVALY SVALKDCCQE MLKNGLVSMN
430 440
NEYLQDLDAV PELDDLSASV YSNFGV