Q758Y7

PR
Gene name
SNX3 (ADR390C)
Protein name
Sorting nexin-3
Names
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_ADR390C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q758Y7

Entry ID Method Resolution Chain Position Source
AF-Q758Y7-F1 Predicted AlphaFoldDB

No variants for Q758Y7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q758Y7

No associated diseases with Q758Y7

1 regional properties for Q758Y7

Type Name Position InterPro Accession
domain Phox homology 34 - 162 IPR001683

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Prevacuolar compartment membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
early endosome membrane The lipid bilayer surrounding an early endosome.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
retromer complex A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol-3-phosphate binding Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.

3 GO annotations of biological process

Name Definition
endocytic recycling The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
late endosome to Golgi transport The directed movement of substances from late endosomes to the Golgi.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRQFQSFSTT VERELAAAPT ARPARTAAGY DEPENFLEVE VRDPRTHFPH GDSNRGMYTD
70 80 90 100 110 120
YLVVCRTNLP SFPQRVSQVR RRYSDFEFFK RCLFKELSLS AHPRVVIPAL PGKILWARRF
130 140 150 160
HDEVIEERRE GLAQWLSTVA GHPLLQSGSK VLVRFLQDEV FNG