Q758U2
Gene name |
SIL1 (AEL340W) |
Protein name |
Nucleotide exchange factor SIL1 |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AEL340W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q758U2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q758U2-F1 | Predicted | AlphaFoldDB |
No variants for Q758U2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q758U2 | |||||
No associated diseases with Q758U2
No regional properties for Q758U2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q758U2 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum lumen | The volume enclosed by the membranes of the endoplasmic reticulum. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| adenyl-nucleotide exchange factor activity | Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| SRP-dependent cotranslational protein targeting to membrane, translocation | The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYWKKLLFAI | ASAAALAAVD | PETEGSELQT | ICSGGECYPR | LFKALQDWST | IKEGQQIPPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LDIRVDLSTG | KKQARLPIPN | EASNMENGIQ | VVDDSSDYEF | TKEFQLVRAQ | VASGAPDYNV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VIKQLDDLVE | YASDYTLGYK | IITHEFTLLQ | ELIFGQDVPI | SVKELSSRII | VACLRNNTPC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDFVNTRFPD | FVRHLLQEAV | DYGRQATDAV | EARTQIKRYL | SIVEPLLINE | PQPINEEALK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QLYEVNDQTV | QLKVLLIMAR | LYKGRSHNDD | ISKRSLESTD | VQRWTTELSK | AIQSKHLDDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HVRELFHGLY | ALKKEHGRAV | KTYPTFLGWL | AEETEARKQR | MTQDKQPRDL | EQMEFDRLLI |
| 370 | 380 | ||||
| ESRHMVFGNP | MAHRIKNMEY | DEL |