Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q757H2

Entry ID Method Resolution Chain Position Source
AF-Q757H2-F1 Predicted AlphaFoldDB

No variants for Q757H2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q757H2

No associated diseases with Q757H2

2 regional properties for Q757H2

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 188 - 347 IPR001251
domain CRAL/TRIO, N-terminal domain 109 - 162 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Endosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endosome A vacuole to which materials ingested by endocytosis are delivered.
lipid droplet An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol transfer activity Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.

6 GO annotations of biological process

Name Definition
Golgi to plasma membrane protein transport The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
negative regulation of fatty acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
negative regulation of phosphatidylglycerol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
phosphatidylinositol metabolic process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
phospholipid catabolic process The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
positive regulation of phosphatidylcholine biosynthetic process Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQTAAPGRV QTLTKEQEKV LKQVWVHLFQ FWGIDVDGSA VLTAKEPEPA APSGKGRKLL
70 80 90 100 110 120
GLFGKRKDAT GAARKESNGK AAAKVYDAEK VEDSDAEKEK PTPQKVEGLE EMYELLKELD
130 140 150 160 170 180
GAAVSKEFWS MLRCDYPDNL LLRFVRARKW DINKAMIMMA HSLRWRLNEG KPEDIVFGGE
190 200 210 220 230 240
RGAQKADKKG IVKQLELGKA TVRGFDKNGC PIVYVRPRLH HAADQTEAET SEYSLLIIEQ
250 260 270 280 290 300
ARLFLKEPCD TATILFDLSG FSMANMDYAP VKFLITCFEA HYPECLGKLF IHKAPWIFPP
310 320 330 340 350 360
IWNIIKNWLD PVVAAKIAFT KTAADLEEFI PAEQIPLELG GKDEYNFDGF VMPDGSADTK
370 380 390 400 410 420
LSDEKGKAAV LEEREAIIKR FIDATISWIE STSDEESAKW LEKKIDLSKE LSENYSKLDP
430
YIRSRSFYDV NGTLKV