Q756K8
Gene name |
CTM1 (AER246W) |
Protein name |
Cytochrome c lysine N-methyltransferase 1 |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AER246W |
EC number |
2.1.1.59: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q756K8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q756K8-F1 | Predicted | AlphaFoldDB |
No variants for Q756K8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q756K8 | |||||
No associated diseases with Q756K8
1 regional properties for Q756K8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SET domain | 32 - 284 | IPR001214 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.59 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| [cytochrome c]-lysine N-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c. |
| protein-lysine N-methyltransferase activity | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| peptidyl-lysine monomethylation | The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRCGWMAGSS | ETVGIMDTAD | WYIGHGQVTV | APCVSIERSQ | IKSPDSGYGV | FVDVDKLQEE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ECEAVELLRV | PYGNVISVRT | LMDWLSGRGD | GYDASKDLIK | TYLALFLEDT | SNHRFVTETN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MLILYLALMA | ILSERGYGFP | DKFVIYLRDV | LLQTRLLTPV | LEVLTQEAGD | AGAHYRNGPQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EIFLSTLLQF | ISGAFMGCTR | AVVLRVYAAV | LSRCLEIPHE | TSPGSEDYTV | SSSLVPILDF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TNHSCEHRNA | YFDVDRESGD | VLLMLDVAAC | AGLGDRFEVF | ISYCPVEELV | HFKHTYGFFP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RASCGTQFWH | MFLSDTWLKE | ERAPHGSGSL | FQIYSELRVL | PYIELALISG | QVYVNDYCSS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FPELLLPFVN | IEALSDKESK | LTALKGDQQL | LAEAKTNFLS | FLARYLDKLV | ANGPIRHSGP |
| 430 | 440 | 450 | 460 | 470 | |
| VCASLRDILL | RELELSKRLR | NTLQHGSAFL | SSHMADTSPP | YCPSPAPSPP | YAYMYTSS |