Q756F2
Gene name |
PPN1 (AER313C) |
Protein name |
Endopolyphosphatase |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AER313C |
EC number |
3.6.1.10: In phosphorus-containing anhydrides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q756F2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q756F2-F1 | Predicted | AlphaFoldDB |
No variants for Q756F2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q756F2 | |||||
No associated diseases with Q756F2
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.1.10 | In phosphorus-containing anhydrides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| fungal-type vacuole | A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. |
| fungal-type vacuole membrane | The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| endopolyphosphatase activity | Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. |
| exopolyphosphatase activity | Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| polyphosphate catabolic process | The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAEEGRRLQ | MKNGEGVGRS | GRPRWALWIA | ALMAGALWWT | VHSDAVALMS | KACGKDAATT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PRAARALRGR | FLHITDIHPD | PLYVEGSSIA | GACHGDPARD | ASDRAGRFGD | AMGGCDAPMD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LMNYTLAWVA | THLRDEIDFV | VWTGDNARHD | NDRRQPRTAE | QILHMNAQVA | DQFYELFQQQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RDGDTMQGVP | VVPSLGNNDV | FPHNMFSLGP | TLMTRQLQRI | WAKFIPEEQR | QAFEHDTSFF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEVIPDRLAV | ISFNTLYFFK | SNPLVDNCND | KAQPGHALLL | WLGSVLEEMR | ARNMKVWLSG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HVPPIPKNFE | GSCYNKLAWW | TYEYRDVIIG | GLYGHMNVDH | FYPADGKAAK | KSIKRRGKAR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TKERNTQEQP | LDILDDSVDN | LFSGRGAMPL | RKEKYMRRLF | KDVYCPIAKR | LEDKGKQEQS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YERYSMVHVA | ASVIPTFNPG | FRVWEYNLTG | IDNAVAPAPW | TRLVRRAQQI | LSPLRKKKHG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PDRTLPPKKP | KHLAAGPGHI | PQALTPIRFT | QYYADLAEIN | KDYARELEAG | RSHDEAAAAA |
| 550 | 560 | 570 | 580 | 590 | |
| FRYKIEYTSE | DEPYPMESLL | VRDYVKLASK | LTEDRTAWKT | YVRRAFVSSG | YRDN |