Q755F7

PR
Gene name
CET1 (AFL134W)
Protein name
mRNA-capping enzyme subunit beta
Names
mRNA 5'-phosphatase, mRNA 5'-triphosphate monophosphatase
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_AFL134W
EC number
3.6.1.74: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

67-148 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q755F7

Entry ID Method Resolution Chain Position Source
AF-Q755F7-F1 Predicted AlphaFoldDB

No variants for Q755F7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q755F7

No associated diseases with Q755F7

3 regional properties for Q755F7

Type Name Position InterPro Accession
domain tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal 22 - 190 IPR011063
domain tRNA(Ile)-lysidine synthase, N-terminal 21 - 194 IPR012795
domain Lysidine-tRNA(Ile) synthetase, C-terminal 348 - 415 IPR012796

Functions

Description
EC Number 3.6.1.74 In phosphorus-containing anhydrides
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mRNA cap methyltransferase complex A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.

2 GO annotations of molecular function

Name Definition
mRNA 5'-phosphatase activity A 5'-end triphospho-
polynucleotide 5'-phosphatase activity Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.

4 GO annotations of biological process

Name Definition
7-methylguanosine mRNA capping Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
polynucleotide 5' dephosphorylation The process of removing one or more phosphate groups from the 5' end of a polynucleotide.
positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
positive regulation of transcription elongation by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSEKQEGSP RRVLSLSDLV NREDSKDASG NTAGAALKPL SNDEVRRRLA HEDYSSNTAS
70 80 90 100 110 120
QVDDETDTDD GLGEVAFDRA DFRFDFEGQE RSGGRASGEA EAESGGPGHE KATQQPSDAI
130 140 150 160 170 180
ATSPDRESTE PRAMDIFEER ASLESKKNNL RKDLRVLNEI ASTARPGRYK VAPIWAQKWK
190 200 210 220 230 240
PTVRALQNVN SKDLMKIDVS FTQVIPDDDL TKSVQDWVYA TLLSIPPEQR QYVEVEMKFG
250 260 270 280 290 300
ILMDRSSDSQ RVTPPVSSQT VYMEADARMK PDVDERVFVE LNRYVKGISE LTENTGKFNI
310 320 330 340 350 360
IESHNKDEMY RAGINTQRPR FLRMSKDVKT GRVGEFIEKR RISQLLLFSP KDSYDVKISI
370 380 390 400 410 420
NVELPVPEND PPEKYMGQAP LNSRTKERIS YIHNDSCTRI DITKVTNHNK GKRDDAEVTH
430 440 450 460 470
EIELELNSQA LLAAFDKIAQ DSKDYATIVR TFLNNGTIIR RKLTSLSYEI FEGGKKVV