Q755C5

PR
Gene name
MRH4 (AFL102W)
Protein name
ATP-dependent RNA helicase MRH4, mitochondrial
Names
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_AFL102W
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-264 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q755C5

Entry ID Method Resolution Chain Position Source
AF-Q755C5-F1 Predicted AlphaFoldDB

No variants for Q755C5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q755C5

No associated diseases with Q755C5

3 regional properties for Q755C5

Type Name Position InterPro Accession
domain Helicase, C-terminal 368 - 554 IPR001650
domain DEAD/DEAH box helicase domain 137 - 324 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 132 - 354 IPR014001

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
mitochondrial ribosomal large subunit rRNA binding Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
mitochondrial large ribosomal subunit assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSVGIASAS LWLRGPVKSA LKGRWLSCEQ MRRYGTKSAP AVRKGGHSKK ARQAPSLPFV
70 80 90 100 110 120
FGRHKQLTGP EFTRRTRIGN LSDKITKFEQ LKLLPEVREV MMKVIASESV LNKSLDDEDC
130 140 150 160 170 180
GLDDKRVAAF LGQVQPTPIQ TAVIKKMAKT LMEPQLQVHM VAAETGSGKT MSYLMPLVDY
190 200 210 220 230 240
LKQEEQAAGT EEGRARLGAL RSLILVPTHE LVEQVYMTLE KLQEPLQLKT FKLDRDTPYK
250 260 270 280 290 300
DIVEAFKGRV DIMVTTPGKL RGLFKIRMLH RPDRILSQVR FAVVDEADTL MDQSWVQETY
310 320 330 340 350 360
SCIKSLRDAN HLVFCSASVP MEFEKAMNKL FPNLQVVASE KLHRINKHSN IKIINVALRP
370 380 390 400 410 420
YNGSKMKALA QALYAIMKDG TSEGYEKRCV VFVNEADSVN SIVDTLRDKF GHDVHGLTGE
430 440 450 460 470 480
HSLDDRLATI APFMRSPPRI QDQVRPSELK KPQERRLPNS NIKVADSKDN GQRSVSSPLK
490 500 510 520 530 540
VLVTTDVLSR GINFKGVKHV ILYDVPAKSI DLVHRVGRTS RMNERGHVYI FVGKKGSAQA
550
KGLNPVVKKN RPIQ