Q754U7
Gene name |
ABD1 (AFL026W) |
Protein name |
mRNA cap guanine-N7 methyltransferase |
Names |
mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase |
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AFL026W |
EC number |
2.1.1.56: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q754U7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q754U7-F1 | Predicted | AlphaFoldDB |
No variants for Q754U7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q754U7 | |||||
No associated diseases with Q754U7
1 regional properties for Q754U7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | mRNA (guanine-N(7))-methyltransferase domain | 96 - 425 | IPR004971 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.56 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mRNA cap binding complex | Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA (guanine-N7-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 7-methylguanosine mRNA capping | Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALRPEKPVW | MSQEQYDRQY | GKLEEPKPPR | EESKPGDQAK | PSAEPKSGSE | EKTEGSSSST |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GQGEERPHFK | IQKRRHQNYD | LEERKKKQQL | NKLREEQLKQ | HDIEMAANKV | VNVDQIVREH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YNERTFHAKR | YNRNYSPIIK | LRNFNNAIKY | MLIDKYTRPR | DVVLELGCGK | GGDLRKYGAC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EISQFIGIDI | SNESIREAQR | RYLNMRDLDY | QVILITGDCF | GESLGVAVQP | FPECRFPCDV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VSTQFCLHYA | FETEEKARRA | ILNVSKSLKV | GGFFFGTIPD | AEFIRYKLNK | FSKEVERPSW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GNSIYKVVFA | NNSYQLNDYE | FETPYGNMYT | YWLEDAIDNV | PEYVIPFETL | RNLCDEYGME |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LEMQKPFNKF | FVEEIPQWMN | KFSPRLREGL | QRSDGKYGVE | GDEKEAASYF | YTVFAFRKVK |
| DYVENAPAHA |