Q754C8

PR
Gene name
EFT1 (AFR142C)
Protein name
Elongation factor 2
Names
EF-2
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_AFR142C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q754C8

Entry ID Method Resolution Chain Position Source
AF-Q754C8-F1 Predicted AlphaFoldDB

No variants for Q754C8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q754C8

No associated diseases with Q754C8

2 regional properties for Q754C8

Type Name Position InterPro Accession
domain Ephrin receptor-binding domain 17 - 151 IPR001799
domain Ephrin-A ectodomain 19 - 145 IPR034252

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

4 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
ribosome binding Binding to a ribosome.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVAFTVDQIR SLMDKVTNVR NMSVIAHVDH GKSTLTDSLV QRAGIISAAK AGEARFTDTR
70 80 90 100 110 120
KDEQERGITI KSTAISLFSE MSEEDVKDIK QKTEGNSFLI NLIDSPGHVD FSSEVTAALR
130 140 150 160 170 180
VTDGALVVVD TVEGVCVQTE TVLRQALGER IKPVVVINKV DRALLELQVS KEDLYQSFSR
190 200 210 220 230 240
TVESVNVIIS TYADEVLGDV QVYPQKGTVA FGSGLHGWAF TIRQFANRYS KKFGVDREKM
250 260 270 280 290 300
MERLWGDSYF NPKTKKWTNK DRDADGKPLE RAFNMFVLDP IFRLFAAIMN FKKDEIPVLL
310 320 330 340 350 360
EKLEIALKSD ERDLEGKALL KVVMRKFLPA ADALLEMIIM HLPSPVTAQN YRAEQLYEGP
370 380 390 400 410 420
SDDPACIAIK NCDPKADLML YVSKMVPTSD KGRFYAFGRV FSGTVKSGQK VRIQGPSFTV
430 440 450 460 470 480
GKKEDLFIKA IQRAVLMMGR FVEPIDDCPA GNIVGLVGID QFLLKTGTLT TFESAHNMKV
490 500 510 520 530 540
MKFSVSPVVQ VAVEVKNAND LPKLVEGLKR LSKSDPCVLT YMSESGEHIV AGTGELHLEI
550 560 570 580 590 600
CLQDLENDHA GIPLKISPPV VAYRETVEGE SSQVALSKSP NKHNRIYLKA QPIDEEVSLA
610 620 630 640 650 660
IEGGKINPRD DFKARARVMA DEYGWDVTDA RKIWCFGPDG NGPNLVVDQT KAVQYLNEIK
670 680 690 700 710 720
DSVVSAFQWA TKEGPIFGEQ MRSVRINLLD VTLHADAIHR GAGQIMPTMR RATYAGFLLA
730 740 750 760 770 780
EPKIQEPVFL VEIQCPEQAV GGIYSVLNRK RGQVVSEEQR PGTPLFTVKA YLPVNESFGF
790 800 810 820 830 840
TGELRQATGG QAFPQMVFDH WATLGTDPLD PTTKAGEIVV EARKRHGLKE NVPGWQEYYD
KL