Q753I0
Gene name |
SLD5 (AFR332W) |
Protein name |
DNA replication complex GINS protein SLD5 |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AFR332W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q753I0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q753I0-F1 | Predicted | AlphaFoldDB |
No variants for Q753I0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q753I0 | |||||
No associated diseases with Q753I0
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| CMG complex | A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. |
| GINS complex | A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks. |
| replication fork protection complex | A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| chromosome segregation | The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. |
| DNA unwinding involved in DNA replication | The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. |
| double-strand break repair via break-induced replication | The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDINIDDILA | DLDRDTTAVG | STPAPAGDDT | TRLDDSAATV | AADYSTLVTH | WCNERVAPEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPYPHTLMAR | VLARLAAQIE | HLETLSTGVL | EQTLDRSAKL | PLLCMEAELE | RLKFVVRSLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RCRLGKIDRF | GLYLRQLDAR | SPGALQTLLS | AQERVYYERH | SAILLKLFNN | AILRHMPAEM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QAVDDTEGSV | SMIDEPEWAR | FVFLYVREPA | PDAPDPLLAV | DDHGQPCYSV | NIPELGEVVD |
| 250 | 260 | ||||
| LAVGGIYIMR | YNVIKDLLMD | GKVVLI |