Q751L7

PR
Gene name
URA7 (AGL320C)
Protein name
CTP synthase
Names
CTP synthetase, UTP--ammonia ligase
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_AGL320C
EC number
6.3.4.2: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

322-392 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q751L7

Entry ID Method Resolution Chain Position Source
AF-Q751L7-F1 Predicted AlphaFoldDB

No variants for Q751L7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q751L7

No associated diseases with Q751L7

3 regional properties for Q751L7

Type Name Position InterPro Accession
domain CTP synthase, N-terminal 2 - 270 IPR017456
domain Glutamine amidotransferase 315 - 554 IPR017926
domain CTP synthase GATase domain 304 - 553 IPR033828

Functions

Description
EC Number 6.3.4.2 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoophidium A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
CTP synthase activity Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.
identical protein binding Binding to an identical protein or proteins.

4 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
CTP biosynthetic process The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
pyrimidine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKYVVVSGGV ISGIGKGVLA SSTGMLLKTL GLKVTSIKID PYMNLDAGTM SPLEHGECFV
70 80 90 100 110 120
LNDGGETDLD LGNYERYLGV TLTKDHNITT GKVYSHVMAK ERKGDYLGKT VQVVPHLTNA
130 140 150 160 170 180
IQDWLERVAR IPVDDSGMEP DVCIIELGGT VGDIESAPFV EALRQFQFRV GRDNFALIHV
190 200 210 220 230 240
SLVPVIHGEQ KTKPTQAAIK DLRSLGLTPD MIACRCSEEL DKPTIEKIAM FCHVGPEQVV
250 260 270 280 290 300
NVHDVASTYH VPLLLLEQRM IDYLGQRLKL SDIKLGAEDK ERGARLLDRW RHLTTAIDES
310 320 330 340 350 360
FEVVQIALVG KYTHLKDSYL SVIKALEHSS MRCKRKLEIV WVEASDLEPE MSASDKEKFQ
370 380 390 400 410 420
QAWKSLSSSD GILVPGGFGT RGTEGMILAA KWARENKIPY LGVCLGLQVA TIEFARHVLG
430 440 450 460 470 480
IADATSSEFY PEVAEDKQVV VYMPEIDKQN MGGTMRLGLR PTIFQEDTDW SIIRKLYGSA
490 500 510 520 530 540
SSVEERHRHR YEINPKMVQK LEEHGLKFVG RDETGTRCEI LELVDHPYYV ATQYHPEYMS
550 560 570
KVLDPSQPFL GLVAAAANIL PSLLAAERAV GARADF