Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q750X2

Entry ID Method Resolution Chain Position Source
AF-Q750X2-F1 Predicted AlphaFoldDB

No variants for Q750X2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q750X2

No associated diseases with Q750X2

5 regional properties for Q750X2

Type Name Position InterPro Accession
domain Zinc finger, CCHC-type 273 - 289 IPR001878-1
domain Zinc finger, CCHC-type 298 - 314 IPR001878-2
domain K Homology domain 147 - 240 IPR004087
domain K Homology domain, type 1 164 - 192 IPR004088
domain Splicing factor 1, helix-hairpin domain 34 - 144 IPR032570

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
commitment complex A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
pre-mRNA branch point binding Binding to a pre-mRNA branch point sequence, located upstream of the 3' splice site.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
regulation of mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRLVWFCMQ VAYCLHGWDW DIMDRGRSSN SYDSLWGGKA RDNPIVSQLP LQYRIRSALT
70 80 90 100 110 120
QEQQTAYQVM YRIQEITIKL RTNDLNPPTS RYRSLSPPPV YDSQGKRTNT REHRYRKKLE
130 140 150 160 170 180
EERHRLVEIA LKMIPHFIAP DDYRRPSKFQ DKYYIPINDY PEINFVGLLL GPRGNTLKQL
190 200 210 220 230 240
QQQSGCKIVI RGRGSVKEGK AATDLPKGAM NMNEPLHCVI SADTEEKIPL GINAVESIII
250 260 270 280 290 300
KAITSPEGQN DLKRGQLREL AVLNGTLRED NRPCPLCGEQ GHKKWECSSN PSLSMTVICQ
310 320 330 340 350 360
RCNQPGHAAR DCTSPLNEFG KRTSDGPEFR ETKKLQQDAP PPSGPVGSHP SAPGSGSANS
370 380 390 400 410 420
GVAPASLHPP GTMAPPGALP PPGSLAAPGT LPPPAALPAP AAPGTLPPPV ALPAPATLPQ
430 440 450 460 470 480
AGVPPAPDAS PAVKTAVPIE GPPAPPQTAP PLRQTAATAS SAGSSQSAQE EPENARNGVE
490 500
KAAPGPPAAV LPPPPPPPPP PPPPPSS