Q750F5
Gene name |
HAT1 (AGL001W) |
Protein name |
Histone acetyltransferase type B catalytic subunit |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AGL001W |
EC number |
2.3.1.48: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q750F5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q750F5-F1 | Predicted | AlphaFoldDB |
No variants for Q750F5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q750F5 | |||||
No associated diseases with Q750F5
No regional properties for Q750F5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q750F5 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.48 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome, telomeric region | The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| histone acetyltransferase complex | A protein complex that possesses histone acetyltransferase activity. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| chromatin binding | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
| H4 histone acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4. |
| histone binding | Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| histone H4 acetylation | The modification of histone H4 by the addition of an acetyl group. |
| subtelomeric heterochromatin assembly | The compaction of chromatin into heterochromatin at the subtelomeric region. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEELKPELW | TTSSNSALKL | SLVNDENAVQ | FSPIFTYPIF | GQAEQLFGYQ | DLNILLAFDS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VTFKPFLNIK | YTKKLERGLD | DVEGSILKFL | PEGDVILKDE | VEWVDAFNGE | REKFALPNSE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SKVAEYTSGG | ESFAIFKVHL | SDPNIRQLHR | RMQIFTLLFI | EAASYIDEDD | SAWDIFMTFN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TSTRQCIGYT | TTYKHWRYIN | GQEFDSSEKT | TKRAKISQFI | IFPPYQSKSH | GSHLYSAAID |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VWSKEEKISE | VTVEDPNEAF | DDLRDRCDFM | RLSGSGLSSS | IPEDVPIPRT | WLTEQARKYK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LSLVQFTRLV | EMILLYDNSP | NFEIQVKARL | YQKNHEVLTG | MDSDTRKAKL | QEAFTSLKED |
| 370 | 380 | 390 | |||
| YARILQKVPN | RRRVLPSDEE | NAGESKRHKK | E |