Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q750A5

Entry ID Method Resolution Chain Position Source
AF-Q750A5-F1 Predicted AlphaFoldDB

No variants for Q750A5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q750A5

No associated diseases with Q750A5

2 regional properties for Q750A5

Type Name Position InterPro Accession
domain Exonuclease, RNase T/DNA polymerase III 222 - 378 IPR013520
domain RNA exonuclease 1-like, exonuclease domain 224 - 370 IPR034922

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
3'-5'-exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.
nucleic acid binding Binding to a nucleic acid.

2 GO annotations of biological process

Name Definition
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
U5 snRNA 3'-end processing Any process involved in forming the mature 3' end of a U5 snRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAVLRPVDMR MQPAPYEGRM KVIHKILEQL QKYRPRKANL EGLAVQWEHE VAKRSSSKHG
70 80 90 100 110 120
YMFNASLLLR DIARHKGNLN RQGRYEAPAP QVSKAEVLAA LRNLVLSEQV LSENGYVTAQ
130 140 150 160 170 180
DALESAAEEK EGLETCVRCL KKFDVRDIMV PTQCQFHVLK EQYNKDMRTF QYRCCGEIGT
190 200 210 220 230 240
SCTPFALGCK TLEHHVFRPC TYAAMSKLLP FRNTRGVEGE TNVLALDCEM AYTSCGYELI
250 260 270 280 290 300
RLTVVEFWTN AVLFDEIVQP LGEIIDLNTQ FSGVHEIDRA VAKTFEEARE VFLSPAMINE
310 320 330 340 350 360
NSILIGHGLE NDLNVLRIIH DKIIDTAILY PNGKFKSSLR NLAFQELSRR IQTGEHDSSE
370 380
DAIAAMDVVK HKLGIPLDRK TW